Effect of vitamin E supplementation on immune status ...

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Title Effect of vitamin E supplementation on immune status and alpha -tocopherol in plasma of piglets
Author(s) M. Hidiroglou, T. R. Batra, E. R. Farnworth, R. J. Frederick Markham
Journal Reproduction, Nutrition, Development
Date 1995
Volume 35
Issue 4
Start page 443
End page 450
Abstract From day 57 of pregnancy, 12 Yorkshire gilts were given a diet without and with 5% rapeseed oil, supplemented with Se 0.1 mg and DL- alpha -tocopherol (as tocopherol acetate) 22 IU/kg feed. Colostrum (day 0) and milk (days 7, 14, 21 and 28 post partum) were sampled from gilts. At farrowing, 3 piglets from each gilt of both groups were injected with alpha -tocopherol 500 IU at birth and 1000 IU at 7 and 14 days old; 3 piglets were injected with saline and used as controls. Blood samples were taken from the newborn piglets at birth and at 7, 14, 21, 28 and 35 days old. alpha -Tocopherol concentrations and antibody titres in colostrum were significantly higher than in the milk. Plasma alpha -tocopherol concentrations and antibody titres to Keyhole limpet haemocyanin of piglets injected with tocopherol were significantly higher than controls. Tocopherol-injected piglets had significantly higher alpha -tocopherol concentrations in spleen, liver, kidney, heart, lung and hip muscle than controls..
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