Experimental feline infectious enteritis in the ...



Title Experimental feline infectious enteritis in the germfree cat. An electron microscopic study
Author(s) Gerald R. Johnson, A. Koestner, M. W. Rohovsky
Journal Pathologia Vet
Date 1967
Volume 4
Start page 275
End page 288
Abstract Selected tissues from 13 germ-free and three specific pathogen-free cats with experimental feline infectious enteritis were examined by electron microscopy. Intestinal lesions, consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae, occurred only in SPF cats. No lesion was demonstrated in the intestine of germ-free cats. The lesions in the lymph nodes, identical in SPF and germ-free cats, consisted of lymphocytic destruction within 72 hours of inoculation and reactive proliferation of reticular cell-macrophages and plasma cells. The preferred designation of feline infectious pan-leucopenia is supported..

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