Experimental vaccination of rainbow trout against ...

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Title Experimental vaccination of rainbow trout against Loma salmonae using a live low-virulence variant of L. salmonae
Author(s) J. G. Sanchez, David J. Speare, R. J. Frederick Markham, S. R. M. Jones
Journal Journal of Fish Biology
Date 2001
Volume 59
Issue 2
Start page 442
End page 448
Abstract The induction of protection against xenoma development by vaccinated (previously exposed to a low-virulence strain of Loma salmonae; n=40) and naive (n=40) rainbow trout (Oncorhynchus mykiss) challenged with the virulent typical strain of L. salmonae, was determined. Prevalence of infection was lower in vaccinated rainbow trout than in the naive fish. Fish that have been vaccinated with L. salmonae SV spores showed significantly lower numbers of xenomas per filament (P<=0.05), from 3 to 6 weeks post exposure (PE). At the peak of the disease, 4 and 6 weeks PE, vaccinated fish had 14 times fewer xenomas than the naive fish (P=0.0001). A single exposure to L. salmonae SV induced protection from disease in juvenile rainbow trout when challenged 15 weeks later with typical, virulent spores..
DOI 10.1006/jfbi.2001.1654

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