Ionophore-mediated inhibition of xenoma-expression ...

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Title Ionophore-mediated inhibition of xenoma-expression in trout challenged with Loma salmonae (Microspora)
Author(s) David J. Speare, J. Daley, P. Dick, M. Novilla, S. Poe
Journal Journal of Fish Diseases
Date 2000
Volume 23
Issue 3
Start page 231
End page 233
Abstract The therapeutic effect of dietary treatment with monensin was examined in 70 rainbow trout experimentally infected with 200 000 spores of L. salmonae. 35 fish were then a commercial diet containing ionophore monensin (10 g of monensin per kg of diet) and the remaining fish were fed the same diet without iodophor monensin. During the trial all fish developed xenomas. However, the rate of xenoma-development in monensin-treated fish was delayed. At 4 weeks after infection, monensin-treated fish were significantly less likely to have xenomas compared with control fish, but this difference disappeared by week 5 after infection..
DOI 10.1046/j.1365-2761.2000.00226.x

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