A lipopolysaccharide-specific bacteriophage for ...
|Title||A lipopolysaccharide-specific bacteriophage for Aeromonas salmonicida|
|Author(s)||E. E. Ishiguro, T. Ainsworth, Darcy H. Shaw, W. W. Kay, T. J. Trust|
|Journal||Canadian Journal of Microbiology|
|Abstract||Cell wall lipopolysaccharide (LPS) was identified as the receptor for the A. salmonicida bacteriophage strain 55R-1. Mutants of A. salmonicida resistant to phage 55R-1 were unable to adsorb phage 55R-1 and were shown to be defective in LPS structure. Purified A. salmonicida LPS inactivated phage 55R-1, but the O-polysaccharide and the core oligosaccharide portions of the LPS were ineffective. These results suggest that lipid A was required for receptor activity. Antibodies directed against LPS also inhibited phage adsorption..|
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