Test characteristics from latent-class models of the ...
|Title||Test characteristics from latent-class models of the California Mastitis Test|
|Author(s)||C. J. Sanford, Gregory P. Keefe, J. Sanchez, R. T. Dingwell, H. W. Barkema, K. E. Leslie, Ian R. Dohoo|
|Journal||Preventive Veterinary Medicine|
|Abstract||We evaluated (using latent-class models) the ability of the California Mastitis Test (CMT) to identify cows with intramammary infections on the day of dry-off. The positive and negative predictive values of this test to identify cows requiring dry-cow antibiotics (i.e. infected) was also assessed. We used 752 Holstein-Friesian cows from 11 herds for this investigation. Milk samples were collected for bacteriology, and the CMT was performed cow-side, prior to milking on the day of dry-off. At the cow-level, the sensitivity and specificity of the CMT (using the four quarter results interpreted in parallel) for identifying all pathogens were estimated at 70 and 48%, respectively. If only major pathogens were considered the sensitivity of the CMT increased to 86%. The negative predictive value of the CMT was >95% for herds with major-pathogen intramammary-infection prevalence <15%, so that selective dry-cow therapy might be reasonable for such herds if cows were screened with the CMT.|
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