Population dynamics of bovine herpesvirus 1 ...
|Title||Population dynamics of bovine herpesvirus 1 infection in a dairy herd|
|Author(s)||J. J. Hage, Y. H. Schukken, H. W. Barkema, G. Benedictus, F. A. Rijsewijk, G. H. Wentink|
|Abstract||An induced outbreak of a bovine herpesvirus 1 (BHV1) infection in a dairy herd is described. The outbreak was induced by injecting three BHV1 seropositive cows with dexamethasone. Within 7 weeks all seronegative cows had seroconverted. Also some seropositive animals showed a significant increase in serum antibody titre. Using these data, parameters of population dynamics such as R0, the basic reproduction ratio, could be estimated. The basic reproduction ratio is a threshold value describing infection dynamics in a population. This parameter is defined as the average number of secondary cases generated by one primary case in a wholly susceptible population of defined density. In this population R0 was estimated to be at least 7. The importance of these findings, and implications for eradication of BHV1 are discussed.|
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