Determination of the excretion time of ...

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Title Determination of the excretion time of oxytetracycline and lugol in milk of intrauterine treated cows
Author(s) T. Dijkstra, H. W. Barkema, R. D. van Buuren, J. G. van Spanje, H. Jorritsma
Journal Tijdschrift voor Diergeneeskunde
Date 1994
Volume 119
Issue 21
Start page 634
End page 636
Abstract Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 micrograms/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 micrograms/kg used by milk-testing stations and the European limit (MRL) of 100 micrograms/kg. Milk from cows treated with lugol did not cause inhibition in the plate test.

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