Comparison of two ELISA screening tests and a ...



Paper title Comparison of two ELISA screening tests and a non-commercial glutaraldehyde coagulation screening test for the detection of failure of passive transfer in neonatal foals
Paper author(s) J. Trenton McClure, J. Miller, J. L. DeLuca
Proceedings title Proceedings of the 49th Annual Convention of the American Association of Equine Practitioners, New Orleans, Louisiana, USA, 21-25 November 2003
Date 2003
Abstract This study evaluated the sensitivity, specificity and positive predictive value/negative predictive value of the CITE ELISA, the first version of the SNAP ELISA, and the revised version of the SNAP ELISA (SNAP ELISA 1 and SNAP ELISA 2, respectively). This study also evaluated a non-commercial version of another popular screening test for failure of passive transfer (FPT), the glutaraldehyde coagulation test (GCT). The results showed that CITE ELISA was unacceptable as a screening test for FPT because of its poor sensitivity and poor NPV. The SNAP ELISA 2 and GCT are more appropriate screening tests, because they have a high sensitivity and NPV. The specificity and PPV of the SNAP ELISA 2 test is better than the GCT..

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