Effects of overfeeding by gastric intubation on body ...
|Title||Effects of overfeeding by gastric intubation on body composition of adult female rats and on heat production during feeding and fasting|
|Author(s)||K. McCracken, M. McNiven|
|Journal||British Journal of Nutrition|
|Abstract||The effects of overfeeding by gastric intubation on body composition and energy metabolism of adult female rats were studied. There were significant linear increases in carcass DM, fat and energy during 10 days as daily metabolizable energy (ME) intake was increased from 160 to 300 kJ. Rats were given daily 130 kJ to maintain weight or about 270 kJ daily for 120 days. Measurements of fed and fasting heat production (FHP) were made at intervals. FHP, kJ/day kg0.75, decreased by 15% in 120 days on either treatment. The mean carcass weight of the overfed rats increased from 216 to 465 g, over 90% of the increase being due to fat. For 6, 12, 18, 24 or 30 days 3 rats were given daily 137 kJ to maintain weight or about 300 kJ. There were significant linear increases with time in carcass weight, DM, fat and energy. FHP measured before slaughter increased from 118 to 160 kJ/day but stayed constant at 334 kJ/day kg0.75. In all the experiments there were significant increases in carcass crude protein (N X 6.25) in response to overfeeding. The efficiency of utilization of energy for production or for maintenance and production averaged 0.92 and 0.86 to 0.88. It is concluded that FHP may be regarded as constant over a wide range of body compositions in adult rats made obese by force-feeding..|
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