A novel biosynthetic route to pregnanes in the ...



Title A novel biosynthetic route to pregnanes in the marine sponge Amphimedon compressa
Author(s) Russell G. Kerr, K. Kelly, A. Schulman
Journal Journal of Natural Products
Date 1995
Volume 58
Issue 7
Start page 1077
End page 1080
Abstract A novel degradative route to pregnanes has been elucidated in the marine sponge Araphimedon compressa. 22-Dehydrosterols, common in the diet of sponges, are the precursors to pregnanes and apparently are degraded by a mechanism analogous to the dealkylation of phytosterols to cholesterol.

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