Robert Hurta

Description

Details

NameRobert Hurta
PositionFaculty Member
Emailrhurta@upei.ca
Department(s)Biology
Phone(902) 566-0476
BuildingDuffy Science Centre 436
Websitehttp://www.upei.ca/biology/hurta

Research Interests

  • Gene Expression
  • Regulation relevant to vascular and cancer cell biology

Grants

Blueberry phytochemicals, the UPA/UPAR signaling network and prostate cancer: an invitro study.
  • Granting Program
  • Motorcycle Ride for Dads

Other Scholars in Biology

Citations

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TitleAuthor(s)
Magnolol affects expression of IGF-1 and associated binding proteins in human prostate cancer cells in vitroMcKeown, Brendan T.; Hurta, Robert A. R.
Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitroMacPhee, James; Stetson, Colin R.; Elwood, Benjamin W.; Patel, Kunal; McCallum, Jason; Neto, Catherine; Hurta, Robert A.R.
Alterations in the cyclic AMP signal transduction pathway regulating ribonucleotide reductase gene expression in malignant H‐ras transformed cell linesHurta, Robert A. R.; Wright, J. A.
Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblastsFrancis, Edward Joseph; Hurta, Robert
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active Mitogen-Activated Protein (MAP) kinase kinaseHurta, Robert A. R.
Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinaseChadee, D. N.; Taylor, W. R.; Hurta, Robert A. R.; Allis, C. D.; Wright, J. A.; Davie, J. R.
Mammalian drug resistant mutants with multiple gene amplifications: Genes encoding the M1 component of ribonucleotide reductase, the M2 component of ribonucleotide reductase, ornithine decarboxylase, p5-8, the H-subunit of ferritin and the L-subunit of ferritinHurta, Robert A. R.; Wright, J. A.
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formationBaruch, R. R.; Melinscak, H.; Lo, J.; Liu, Y.; Yeung, O.; Hurta, Robert A. R.
Regulation of ornithine decarboxylase (ODC) and spermidineMatchett, M. D.; Hurta, Robert A. R.
Correlation between levels of ferritin and the iron-containing component of ribonucleotide reductase in hydroxyurea-sensitive,hydroxyurea-resistant, and hydroxyurea-revertant cell linesHurta, Robert A. R.; Wright, J. A.
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell linesVoskas, D.; Mader, R.; Lee, J.; Hurta, Robert A. R.
Salt compounds as control agents of late blight and pink rot of potatoes in storageMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
Early induction of ribonucleotide reductase gene expression by transforming growth factor beta 1 in malignant H-ras transformed cell lines.Hurta, Robert A. R.; Samuel, S. K.; Greenberg, A. H.; Wright, J. A.
Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H‐ras transformed cell linesHurta, Robert A. R.; Wright, J. A.
K-FGF mediated transformation and induction of metastatic potential involves altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression - role in cellular invasionHardin, M. S.; Mader, R.; Hurta, Robert A. R.
Phorbol ester tumour mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formationYeung, O.; Hurta, Robert A. R.
Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesisWright, J. A.; Chan, A. K.; Choy, B. K.; Hurta, Robert A. R.; Mcclarty, G. A.; Tagger, A. Y.
Matrix metalloproteinase expression in transformed cells.Baruch, R. R.; Hurta, Robert A. R.
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).Samuel, S. K.; Hurta, Robert A. R.; Kondaiah, P.; Khalil, N.; Turley, E. A.; Wright, J. A.; Greenberg, A. H.
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell linesVoskas, D.; Kim, M.; Hurta, Robert A. R.
Basic fibroblast growth factor selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed cellsHurta, Robert A. R.; Huang, A. P.; Wright, J. A.
Amplification of the genes for both components of ribonucleotide reductase in hydroxyurea resistant mammalian cellsHurta, Robert A. R.; Wright, J. A.
Altered regulation of message stability and tumor promoter-responsive cis-trans interactions of ribonucleotide reductase R1 and R2 messenger RNAs in hydroxyurea-resistant cellsAmara, F. M.; Hurta, Robert A. R.; Huang, A. P.; Wright, J. A.
Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cellsMacLean, Malcolm Adam; Matchett, Michael David; Amoroso, Jon; Neto, Catherine; Hurta, Robert
Malignant transformation by H‐ras results in aberrant regulation of ribonucleotide reductase gene expression by transforming growth factor‐β1Hurta, Robert A. R.; Wright, J. A.
Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta(1)Hurta, Robert A. R.; Lee, J.; Voskas, D.
Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblastsFrancis, E. J.; Hurta, R. A. R.
IGF-1 and IGF-2 mediated expression and regulation of ornithine decarboxylase and spermidineHurta, Robert A. R.; Matchett, M. D.
Transforming growth factor‐β1 mediated alterations in ribonucleotide reductase gene expression in BALBHurta, Robert A. R.; Greenberg, A. H.; Wright, J. A.
Altered expressionHurta, Robert A. R.
Over-expression of K-FGF or bFGF results in altered expression of matrix metalloproteinasesLo, J.; Hurta, Robert A. R.
Lipopolysaccharide, cranberry flavonoids, and regulation of ornithine decarboxylase [ODC] and spermidineMatchett, M. D.; Compton, K. A.; Kondo, M.; Neto, C. C.; Hurta, Robert A. R.
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancyBielecki, D.; Hurta, Robert A. R.
Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin AHurta, Robert A. R.; Wright, J. A.
Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent.Hurta, Robert A. R.; Wright, J. A.
S-adenosytmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progressionHurta, Robert A. R.
Growth factor-mediated altered expression and regulation of S-adenosylmethionine decarboxylase in a H-ras transformed cell line capable of malignant progressionHardin, M. S.; Hurta, Robert A. R.
TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan.Samuel, S. K.; Hurta, Robert A. R.; Spearman, M. A.; Wright, J. A.; Turley, E. A.; Greenberg, A. H.
Relief of temperature sensitivity in a concanavalin A resistant Chinese hamster ovary cell line auxotrophic for cholesterolHurta, Robert A. R.; Burton, D. N.
Effect of salt compounds on mycelial growth, sporulation and spore germination of various potato pathogensMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cellsYoon, A.; Hurta, Robert A. R.
Sensitivity of Erwinia spp. to salt compounds in vitro and their effect on the development of soft rot in potato tubers in storageMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
Transforming growth factor beta(1) selectively regulates ferritin gene expression in malignant H-ras-transformed fibrosarcoma cell linesLo, J.; Hurta, Robert A. R.
Transforming growth factor β1 selectively regulates ornithine decarboxylase gene expression in malignant H‐ras transformed fibrosarcoma cell linesHurta, Robert A. R.; Greenberg, A. H.; Wright, J. A.
American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulatorsDeziel, B.; MacPhee, J.; Patel, K.; Catalli, A.; Kulka, M.; Neto, C.; Gottschall-Pass, K.; Hurta, R.
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium)Matchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Flavonoids from lowbush blueberry decrease matrix metalloproteinase activity in human prostate cancer cellsMatchett, M. D.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Blueberry flavonoids inhibit matrix metalloproteinase activity in DU145 human prostate cancer cellsMatchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitroNeto, C. C.; Krueger, C. G.; Lamoureaux, T. L.; Kondo, M.; Vaisberg, A. J.; Hurta, Robert A. R.; Curtis, S.; Matchett, M. D.; Yeung, H.; Sweeney-Nixon, Marva I.; Reed, J. D.
Protective effects of flavonoids from cranberry on rat neurons and vascular cells.Neto, C. C.; Kondo, M.; Lamoureaux, T. L.; Sweeney-Nixon, Marva I.; Curtis, S.; Hurta, Robert A. R.
Proanthocyanidins, anthocyanins, and triterpenoids from cranberry fruitsKondo, M.; Lamoureaux, T. L.; Neto, C. C.; Hurta, Robert A. R.; Curtis, S.; Matchett, M. D.; Yeung, H.; Sweeney-Nixon, Marva I.; Vaisberg, A. J.
Protective effects of flavonoids from cranberries on rat neurons and vascular cells.Neto, C. C.; Kondo, M.; Sweeney-Nixon, Marva I.; Hurta, Robert A. R.
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cellsMacDougall, Colleen; Amoroso, Jon; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathwaysDeziel, Bob A.; Patel, Kunal; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert A. R.

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TitleTimes viewedLast viewed
Alterations in the cyclic AMP signal transduction pathway regulating ribonucleotide reductase gene expression in malignant H‐ras transformed cell lines - ir:ir-batch6-109925406:58:31 2014-12-18
Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblasts - ir:87135506:07:23 2014-12-17
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active Mitogen-Activated Protein (MAP) kinase kinase - ir:ir-batch6-108927503:20:57 2014-12-14
Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase - ir:ir-batch6-109626503:04:38 2014-12-17
Mammalian drug resistant mutants with multiple gene amplifications: Genes encoding the M1 component of ribonucleotide reductase, the M2 component of ribonucleotide reductase, ornithine decarboxylase, p5-8, the H-subunit of ferritin and the L-subunit of ferritin - ir:ir-batch6-110924221:06:08 2014-12-13
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formation - ir:ir-batch6-108430001:47:05 2014-12-18
Regulation of ornithine decarboxylase (ODC) and spermidine - ir:ir-batch6-107328001:06:20 2014-12-18
Correlation between levels of ferritin and the iron-containing component of ribonucleotide reductase in hydroxyurea-sensitive,hydroxyurea-resistant, and hydroxyurea-revertant cell lines - ir:ir-batch6-110727702:35:02 2014-12-18
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines - ir:ir-batch6-108826608:25:11 2014-12-09
Salt compounds as control agents of late blight and pink rot of potatoes in storage - ir:ir-batch6-107129203:22:39 2014-12-18
Early induction of ribonucleotide reductase gene expression by transforming growth factor beta 1 in malignant H-ras transformed cell lines. - ir:ir-batch6-110626706:25:15 2014-12-16
Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H‐ras transformed cell lines - ir:ir-batch6-109827500:04:19 2014-12-17
K-FGF mediated transformation and induction of metastatic potential involves altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression - role in cellular invasion - ir:ir-batch6-108026609:52:32 2014-12-18
Phorbol ester tumour mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation - ir:ir-batch6-108529217:45:16 2014-12-17
Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis - ir:ir-batch6-110826110:00:51 2014-12-18
Matrix metalloproteinase expression in transformed cells. - ir:ir-batch6-109327720:08:24 2014-12-13
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225). - ir:ir-batch6-110426701:39:31 2014-12-18
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell lines - ir:ir-batch6-108326221:57:46 2014-12-15
Basic fibroblast growth factor selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed cells - ir:ir-batch6-109429303:09:23 2014-12-12
Amplification of the genes for both components of ribonucleotide reductase in hydroxyurea resistant mammalian cells - ir:ir-batch6-111028000:13:56 2014-12-14
Altered regulation of message stability and tumor promoter-responsive cis-trans interactions of ribonucleotide reductase R1 and R2 messenger RNAs in hydroxyurea-resistant cells - ir:ir-batch6-109527501:14:06 2014-12-18
Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cells - ir:89236315:25:15 2014-12-14
Malignant transformation by H‐ras results in aberrant regulation of ribonucleotide reductase gene expression by transforming growth factor‐β1 - ir:ir-batch6-109727609:58:06 2014-12-17
Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta(1) - ir:ir-batch6-108728104:48:54 2014-12-18
Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblasts - ir:87029005:28:18 2014-12-18
IGF-1 and IGF-2 mediated expression and regulation of ornithine decarboxylase and spermidine - ir:ir-batch6-106925321:38:01 2014-12-13
Transforming growth factor‐β1 mediated alterations in ribonucleotide reductase gene expression in BALB - ir:ir-batch6-110327108:47:03 2014-12-18
Altered expression - ir:ir-batch6-109224406:28:34 2014-12-16
Over-expression of K-FGF or bFGF results in altered expression of matrix metalloproteinases - ir:ir-batch6-107928000:52:33 2014-12-18
Lipopolysaccharide, cranberry flavonoids, and regulation of ornithine decarboxylase [ODC] and spermidine - ir:ir-batch6-107433604:56:52 2014-12-14
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancy - ir:ir-batch6-109026206:44:27 2014-12-18
Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin A - ir:ir-batch6-110224009:45:46 2014-12-14
Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent. - ir:ir-batch6-110525902:10:50 2014-12-18
S-adenosytmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression - ir:ir-batch6-108627107:18:48 2014-12-13
Growth factor-mediated altered expression and regulation of S-adenosylmethionine decarboxylase in a H-ras transformed cell line capable of malignant progression - ir:ir-batch6-108125619:27:17 2014-12-17
TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan. - ir:ir-batch6-110025522:45:37 2014-12-14
Relief of temperature sensitivity in a concanavalin A resistant Chinese hamster ovary cell line auxotrophic for cholesterol - ir:ir-batch6-111128105:58:25 2014-12-15
Effect of salt compounds on mycelial growth, sporulation and spore germination of various potato pathogens - ir:ir-batch6-107727912:18:44 2014-12-16
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells - ir:ir-batch6-108226705:57:01 2014-12-12
Sensitivity of Erwinia spp. to salt compounds in vitro and their effect on the development of soft rot in potato tubers in storage - ir:ir-batch6-106830409:33:29 2014-12-18
Transforming growth factor beta(1) selectively regulates ferritin gene expression in malignant H-ras-transformed fibrosarcoma cell lines - ir:ir-batch6-109126600:08:12 2014-12-18
Transforming growth factor β1 selectively regulates ornithine decarboxylase gene expression in malignant H‐ras transformed fibrosarcoma cell lines - ir:ir-batch6-110125511:09:47 2014-12-18
Magnolol affects expression of IGF-1 and associated binding proteins in human prostate cancer cells in vitro - ir:108485801:47:01 2014-12-18
Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro - ir:109235605:22:24 2014-12-18
American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators - ir:556439009:32:51 2014-12-18
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium) - ir:ir-batch6-126935716:17:36 2014-12-14
Flavonoids from lowbush blueberry decrease matrix metalloproteinase activity in human prostate cancer cells - ir:ir-batch6-107838800:02:02 2014-12-17
Blueberry flavonoids inhibit matrix metalloproteinase activity in DU145 human prostate cancer cells - ir:ir-batch6-126835010:28:57 2014-12-18
MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitro - ir:ir-batch6-107034402:24:42 2014-12-14
Protective effects of flavonoids from cranberry on rat neurons and vascular cells. - ir:ir-batch6-107631007:11:31 2014-12-15
Proanthocyanidins, anthocyanins, and triterpenoids from cranberry fruits - ir:ir-batch6-107530811:51:10 2014-12-16
Protective effects of flavonoids from cranberries on rat neurons and vascular cells. - ir:ir-batch6-107227023:04:27 2014-12-15
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cells - ir:89140006:06:41 2014-12-18
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways - ir:86142922:57:48 2014-12-16