Robert Hurta

Description

Details

NameRobert Hurta
PositionFaculty Member
Emailrhurta@upei.ca
Department(s)Biology
Phone(902) 566-0476
BuildingDuffy Science Centre 436
Websitehttp://www.upei.ca/biology/hurta

Research Interests

  • Gene Expression
  • Regulation relevant to vascular and cancer cell biology

Grants

Blueberry phytochemicals, the UPA/UPAR signaling network and prostate cancer: an invitro study.
  • Granting Program
  • Motorcycle Ride for Dads

Other Scholars in Biology

Citations

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TitleAuthor(s)
Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cellsMacLean, Malcolm Adam; Matchett, Michael David; Amoroso, Jon; Neto, Catherine; Hurta, Robert
IGF-1 and IGF-2 mediated expression and regulation of ornithine decarboxylase and spermidineHurta, Robert A. R.; Matchett, M. D.
Altered expressionHurta, Robert A. R.
Lipopolysaccharide, cranberry flavonoids, and regulation of ornithine decarboxylase [ODC] and spermidineMatchett, M. D.; Compton, K. A.; Kondo, M.; Neto, C. C.; Hurta, Robert A. R.
Sensitivity of Erwinia spp. to salt compounds in vitro and their effect on the development of soft rot in potato tubers in storageMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
Effect of salt compounds on mycelial growth, sporulation and spore germination of various potato pathogensMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblastsFrancis, Edward Joseph; Hurta, Robert
Regulation of ornithine decarboxylase (ODC) and spermidineMatchett, M. D.; Hurta, Robert A. R.
Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblastsFrancis, E. J.; Hurta, R. A. R.
Over-expression of K-FGF or bFGF results in altered expression of matrix metalloproteinasesLo, J.; Hurta, Robert A. R.
K-FGF mediated transformation and induction of metastatic potential involves altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression - role in cellular invasionHardin, M. S.; Mader, R.; Hurta, Robert A. R.
Growth factor-mediated altered expression and regulation of S-adenosylmethionine decarboxylase in a H-ras transformed cell line capable of malignant progressionHardin, M. S.; Hurta, Robert A. R.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cellsYoon, A.; Hurta, Robert A. R.
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell linesVoskas, D.; Kim, M.; Hurta, Robert A. R.
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formationBaruch, R. R.; Melinscak, H.; Lo, J.; Liu, Y.; Yeung, O.; Hurta, Robert A. R.
Phorbol ester tumour mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formationYeung, O.; Hurta, Robert A. R.
S-adenosytmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progressionHurta, Robert A. R.
Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta(1)Hurta, Robert A. R.; Lee, J.; Voskas, D.
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell linesVoskas, D.; Mader, R.; Lee, J.; Hurta, Robert A. R.
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active Mitogen-Activated Protein (MAP) kinase kinaseHurta, Robert A. R.
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancyBielecki, D.; Hurta, Robert A. R.
Transforming growth factor beta(1) selectively regulates ferritin gene expression in malignant H-ras-transformed fibrosarcoma cell linesLo, J.; Hurta, Robert A. R.
Matrix metalloproteinase expression in transformed cells.Baruch, R. R.; Hurta, Robert A. R.
Basic fibroblast growth factor selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed cellsHurta, Robert A. R.; Huang, A. P.; Wright, J. A.
Altered regulation of message stability and tumor promoter-responsive cis-trans interactions of ribonucleotide reductase R1 and R2 messenger RNAs in hydroxyurea-resistant cellsAmara, F. M.; Hurta, Robert A. R.; Huang, A. P.; Wright, J. A.
Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinaseChadee, D. N.; Taylor, W. R.; Hurta, Robert A. R.; Allis, C. D.; Wright, J. A.; Davie, J. R.
Malignant transformation by H‐ras results in aberrant regulation of ribonucleotide reductase gene expression by transforming growth factor‐β1Hurta, Robert A. R.; Wright, J. A.
Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H‐ras transformed cell linesHurta, Robert A. R.; Wright, J. A.
Alterations in the cyclic AMP signal transduction pathway regulating ribonucleotide reductase gene expression in malignant H‐ras transformed cell linesHurta, Robert A. R.; Wright, J. A.
TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan.Samuel, S. K.; Hurta, Robert A. R.; Spearman, M. A.; Wright, J. A.; Turley, E. A.; Greenberg, A. H.
Transforming growth factor β1 selectively regulates ornithine decarboxylase gene expression in malignant H‐ras transformed fibrosarcoma cell linesHurta, Robert A. R.; Greenberg, A. H.; Wright, J. A.
Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin AHurta, Robert A. R.; Wright, J. A.
Transforming growth factor‐β1 mediated alterations in ribonucleotide reductase gene expression in BALBHurta, Robert A. R.; Greenberg, A. H.; Wright, J. A.
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).Samuel, S. K.; Hurta, Robert A. R.; Kondaiah, P.; Khalil, N.; Turley, E. A.; Wright, J. A.; Greenberg, A. H.
Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent.Hurta, Robert A. R.; Wright, J. A.
Early induction of ribonucleotide reductase gene expression by transforming growth factor beta 1 in malignant H-ras transformed cell lines.Hurta, Robert A. R.; Samuel, S. K.; Greenberg, A. H.; Wright, J. A.
Correlation between levels of ferritin and the iron-containing component of ribonucleotide reductase in hydroxyurea-sensitive,hydroxyurea-resistant, and hydroxyurea-revertant cell linesHurta, Robert A. R.; Wright, J. A.
Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesisWright, J. A.; Chan, A. K.; Choy, B. K.; Hurta, Robert A. R.; Mcclarty, G. A.; Tagger, A. Y.
Mammalian drug resistant mutants with multiple gene amplifications: Genes encoding the M1 component of ribonucleotide reductase, the M2 component of ribonucleotide reductase, ornithine decarboxylase, p5-8, the H-subunit of ferritin and the L-subunit of ferritinHurta, Robert A. R.; Wright, J. A.
Amplification of the genes for both components of ribonucleotide reductase in hydroxyurea resistant mammalian cellsHurta, Robert A. R.; Wright, J. A.
Relief of temperature sensitivity in a concanavalin A resistant Chinese hamster ovary cell line auxotrophic for cholesterolHurta, Robert A. R.; Burton, D. N.
Salt compounds as control agents of late blight and pink rot of potatoes in storageMills, A. A. S.; Platt, H. W.; Hurta, Robert A. R.
American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulatorsDeziel, B.; MacPhee, J.; Patel, K.; Catalli, A.; Kulka, M.; Neto, C.; Gottschall-Pass, K.; Hurta, R.
Protective effects of flavonoids from cranberry on rat neurons and vascular cells.Neto, C. C.; Kondo, M.; Lamoureaux, T. L.; Sweeney-Nixon, Marva I.; Curtis, S.; Hurta, Robert A. R.
Proanthocyanidins, anthocyanins, and triterpenoids from cranberry fruitsKondo, M.; Lamoureaux, T. L.; Neto, C. C.; Hurta, Robert A. R.; Curtis, S.; Matchett, M. D.; Yeung, H.; Sweeney-Nixon, Marva I.; Vaisberg, A. J.
Protective effects of flavonoids from cranberries on rat neurons and vascular cells.Neto, C. C.; Kondo, M.; Sweeney-Nixon, Marva I.; Hurta, Robert A. R.
Flavonoids from lowbush blueberry decrease matrix metalloproteinase activity in human prostate cancer cellsMatchett, M. D.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitroNeto, C. C.; Krueger, C. G.; Lamoureaux, T. L.; Kondo, M.; Vaisberg, A. J.; Hurta, Robert A. R.; Curtis, S.; Matchett, M. D.; Yeung, H.; Sweeney-Nixon, Marva I.; Reed, J. D.
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium)Matchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Blueberry flavonoids inhibit matrix metalloproteinase activity in DU145 human prostate cancer cellsMatchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cellsMacDougall, Colleen; Amoroso, Jon; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathwaysDeziel, Bob A.; Patel, Kunal; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert A. R.

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TitleTimes viewedLast viewed
Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cells - ir:8927501:00:55 2013-05-20
IGF-1 and IGF-2 mediated expression and regulation of ornithine decarboxylase and spermidine - ir:ir-batch6-10697113:34:30 2013-05-18
Altered expression - ir:ir-batch6-10927016:59:33 2013-05-19
Lipopolysaccharide, cranberry flavonoids, and regulation of ornithine decarboxylase [ODC] and spermidine - ir:ir-batch6-10749010:51:56 2013-05-18
Sensitivity of Erwinia spp. to salt compounds in vitro and their effect on the development of soft rot in potato tubers in storage - ir:ir-batch6-10687023:56:26 2013-05-19
Effect of salt compounds on mycelial growth, sporulation and spore germination of various potato pathogens - ir:ir-batch6-10777901:13:09 2013-05-19
Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblasts - ir:8718017:28:29 2013-05-11
Regulation of ornithine decarboxylase (ODC) and spermidine - ir:ir-batch6-10737519:40:35 2013-05-19
Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblasts - ir:8707800:36:43 2013-05-15
Over-expression of K-FGF or bFGF results in altered expression of matrix metalloproteinases - ir:ir-batch6-10797322:03:22 2013-05-18
K-FGF mediated transformation and induction of metastatic potential involves altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression - role in cellular invasion - ir:ir-batch6-10806722:38:43 2013-05-19
Growth factor-mediated altered expression and regulation of S-adenosylmethionine decarboxylase in a H-ras transformed cell line capable of malignant progression - ir:ir-batch6-10816912:13:03 2013-05-16
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells - ir:ir-batch6-10826720:12:21 2013-05-18
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell lines - ir:ir-batch6-10836918:01:55 2013-05-19
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formation - ir:ir-batch6-10847923:16:58 2013-05-17
Phorbol ester tumour mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation - ir:ir-batch6-10857202:48:16 2013-05-17
S-adenosytmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression - ir:ir-batch6-10867003:10:07 2013-05-15
Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta(1) - ir:ir-batch6-10877521:13:35 2013-05-18
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines - ir:ir-batch6-10887116:44:27 2013-05-19
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active Mitogen-Activated Protein (MAP) kinase kinase - ir:ir-batch6-10897012:28:38 2013-05-18
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancy - ir:ir-batch6-10907013:08:09 2013-05-19
Transforming growth factor beta(1) selectively regulates ferritin gene expression in malignant H-ras-transformed fibrosarcoma cell lines - ir:ir-batch6-10916502:58:30 2013-05-14
Matrix metalloproteinase expression in transformed cells. - ir:ir-batch6-10938522:12:57 2013-05-18
Basic fibroblast growth factor selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed cells - ir:ir-batch6-10948917:34:38 2013-05-19
Altered regulation of message stability and tumor promoter-responsive cis-trans interactions of ribonucleotide reductase R1 and R2 messenger RNAs in hydroxyurea-resistant cells - ir:ir-batch6-10957310:46:09 2013-05-19
Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase - ir:ir-batch6-10967412:03:49 2013-05-11
Malignant transformation by H‐ras results in aberrant regulation of ribonucleotide reductase gene expression by transforming growth factor‐β1 - ir:ir-batch6-10977220:52:04 2013-05-18
Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H‐ras transformed cell lines - ir:ir-batch6-10987414:39:10 2013-05-19
Alterations in the cyclic AMP signal transduction pathway regulating ribonucleotide reductase gene expression in malignant H‐ras transformed cell lines - ir:ir-batch6-10997210:28:40 2013-05-19
TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan. - ir:ir-batch6-11006906:18:05 2013-05-13
Transforming growth factor β1 selectively regulates ornithine decarboxylase gene expression in malignant H‐ras transformed fibrosarcoma cell lines - ir:ir-batch6-11016223:39:44 2013-05-19
Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin A - ir:ir-batch6-11026614:46:10 2013-05-14
Transforming growth factor‐β1 mediated alterations in ribonucleotide reductase gene expression in BALB - ir:ir-batch6-11037109:16:08 2013-05-19
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225). - ir:ir-batch6-11047922:44:49 2013-05-19
Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent. - ir:ir-batch6-11057812:18:23 2013-05-17
Early induction of ribonucleotide reductase gene expression by transforming growth factor beta 1 in malignant H-ras transformed cell lines. - ir:ir-batch6-11066802:52:50 2013-05-17
Correlation between levels of ferritin and the iron-containing component of ribonucleotide reductase in hydroxyurea-sensitive,hydroxyurea-resistant, and hydroxyurea-revertant cell lines - ir:ir-batch6-11077106:27:04 2013-05-16
Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis - ir:ir-batch6-11087416:15:38 2013-05-18
Mammalian drug resistant mutants with multiple gene amplifications: Genes encoding the M1 component of ribonucleotide reductase, the M2 component of ribonucleotide reductase, ornithine decarboxylase, p5-8, the H-subunit of ferritin and the L-subunit of ferritin - ir:ir-batch6-11097008:24:31 2013-05-12
Amplification of the genes for both components of ribonucleotide reductase in hydroxyurea resistant mammalian cells - ir:ir-batch6-11107507:22:06 2013-05-13
Relief of temperature sensitivity in a concanavalin A resistant Chinese hamster ovary cell line auxotrophic for cholesterol - ir:ir-batch6-11118020:32:58 2013-05-10
Salt compounds as control agents of late blight and pink rot of potatoes in storage - ir:ir-batch6-10718710:08:21 2013-05-19
Protective effects of flavonoids from cranberry on rat neurons and vascular cells. - ir:ir-batch6-10767509:12:44 2013-05-18
Proanthocyanidins, anthocyanins, and triterpenoids from cranberry fruits - ir:ir-batch6-10756908:15:35 2013-05-17
Protective effects of flavonoids from cranberries on rat neurons and vascular cells. - ir:ir-batch6-10726518:38:13 2013-05-19
Flavonoids from lowbush blueberry decrease matrix metalloproteinase activity in human prostate cancer cells - ir:ir-batch6-107810322:16:55 2013-05-18
American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators - ir:55643414:04:25 2013-05-19
MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitro - ir:ir-batch6-10709513:09:54 2013-05-18
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium) - ir:ir-batch6-12699220:55:07 2013-05-19
Blueberry flavonoids inhibit matrix metalloproteinase activity in DU145 human prostate cancer cells - ir:ir-batch6-12689917:08:12 2013-05-19
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cells - ir:8919904:13:46 2013-05-17
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways - ir:8619323:01:49 2013-05-19