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A collection of graduate theses by UPEI masters and doctoral students.

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1 - 25 of 38
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The present ecological crisis reflects a crisis in human consciousness, especially in the western world, where our relationship with the earth and cosmos has been largely shaped and influenced by the stories we have been told in our culture. The old stories, as manifested in the myths and world view...
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This thesis addresses issues of islandness and island identity in the fiction of Cape Breton's Alistair MacLeod and Newfoundland's Wayne Johnston. Through careful readings of their fiction, with supplementary evidence culled from biographical and secondary sources, the thesis shows that their work i...
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To secure the safety of international trade of animal and their derived products, it is required that animals should be proven infection-free using a validated diagnostic test certified by the World Organization for Animal Health (OIE). Test validation involves a multi-step evaluation process to as...
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Cette étude qualitative comporte deux objectifs: 1) examiner les raisons qui motivent le choix d’un établissement postsecondaire chez sept finissants d’une école de langue française dans la région Évangéline à l’Île-du-Prince-Édouard; et 2) explorer l’expérience vécue par ces jeu...
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There is limited scientific information on relationships among smallholder dairy group membership duration, sustainable livelihoods, food and nutrition security in developing countries, and whether nutrition education of women dairy farmers enhances the nutritional benefits of being a dairy group me...
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The objectives of this thesis were: 1) to determine which factors and biological samples were associated with the estimated amount of total arsenic (As) consumed from water and food; 2) to determine which factors were associated with the concentration of total and speciated As ([As]) in urine; 3) to...
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The Newfoundland and Labrador (NL) aquaculture industry is a major contributor of salmon products that help meet protein needs for the world’s growing population. The industry in NL continues to grow and evolve and now includes emerging species in its production such as Atlantic cod. In a growing ...
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The Atlantic Canadian aquaculture industry is dominated by Atlantic salmon production. In recent years, infectious disease, parasitic infestations, and price fluctuations from international competition have caused disruptions to the industry. Diversification of the industry away from Atlantic salmon...
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Syndromic surveillance is a tool for continuous, automated extraction of surveillance information from health data sources. The research documented in this dissertation aimed at exploring informatics and data mining tools in order to develop and implement techniques to harvest additional surveillanc...
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The host parasite system of the MSX parasite, Haplosporidium nelsoni, in the eastern oyster, Crassostrea virginica, poses many challenges for experimental study. The interactions that are involved in the development of the typically high prevalence and intensities of disease encountered in certain e...
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Natural products have long been recognized for their medicinal value in traditional medicine and remain an important component of modern drug discovery. Known for their immense structural diversity, natural products are secondary metabolites that often exhibit unique pharmacological properties. In t...
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The United Nations Convention on the Law of the Sea (UNCLOS) contained a specific section for “Archipelagic States” (Part IV) which are given many rights under the archipelagic regime including, if desired, to designate archipelagic sea lanes (ASLs) through their archipelagic waters. While desig...
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This thesis brings together the study of islands, anthropology, and postcolonialism; it discusses (1) how global assemblages, such as colonial interactions and neoliberal economies influence individual well-being and local health care ontologies as practice on islands, and (2) the space and place of...
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This thesis reviews the development and use of watermills from antiquity to the present, including the economic, environmental and social significance of milling during this time. More specifically, it explores the rise and fall of water-powered technology on two small islands with quite different w...
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Alcyonacean octocorals (Order Alcyonacea, amended from Order, Gorgoniidae) are both dominant on Caribbean reefs and prolific sources of bioactive natural products. Although extensive literature has been published with respect to stony coral-associated bacteria, very little is known regarding bacteri...
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The field of fungal taxonomy has been enduring in recent years due to the progress and application of molecular tools used in concert with morphological analysis. The fungal kingdom is extremely diverse and estimated to include 1.5 million species. Only 11% of these fungi are currently described in ...
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In controlled release, each patient’s body displays different pharmacokinetics for the degradation of the drug delivery system affecting the release of the bioactive compound. The proposed research aims to develop polymeric systems based on a host/guest core capable of indicating controlled releas...
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BACKGROUND Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy (HCM). Human patients with HCM have high serum concentrations of biomarkers of collagen synthesis, indicating a profibrotic state. This abnormality exists in sarcomere mutation carriers both with and without overt left ventr...
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Marine invertebrates, including octocorals, are a prolific source of marine natural products (MNPs) and are also known to host diverse microbial communities. It is well-established that marine microbes are producers of bioactive secondary metabolites. Accordingly, it is hypothesized that bioactive m...
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Schizophrenia is a devastating neurological disorder that affects approximately 1% of the population and is characterized by positive, negative, and/or cognitive symptoms. Positive symptoms are associated with increased glutamate (Glu) and/or dopamine (DA) signaling in the nucleus accumbens (NAcc) w...
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The purpose of this study is to describe the geographic distribution of Aboriginal people who live in remote, isolated Aboriginal communities in Canada in terms of how geographic settings and features, particularly those that are characteristic of island dwellers, are related to and can impact aspec...
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The emergence of Caribbean small island states (SIS) through the 'demonstration effect‘ has resulted in even some of the smallest Caribbean islands achieving sovereignty. Past conventional security threats, such as the 1983 coup and intervention in Grenada, have resulted in the US Commonwealth Car...
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The purpose of this research was to evaluate herd and cow-level Mycobacterium avium subspecies paratuberculosis (MAP) diagnostic tests within non-infected and low to moderate within-herd prevalence MAP-infected herds. Specific objectives were to estimate herd-level sensitivity and specificity of env...
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Approximately 60% of human pathogens and emerging infectious diseases are zoonotic. Simulation models are increasingly being used to investigate the spread of diseases, evaluate intervention strategies and guide the decisions of policy makers. In this thesis a systematic review of modeling methods a...
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Mast cells are crucial effector cells in host defense and immunoregulation. They are equipped with an impressive array of receptor systems which allows them to rapidly respond to pathogen-associated signals. G protein-coupled receptors (GPCRs) mediate mast cell activation and mediator release in res...