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A collection of graduate theses by UPEI masters and doctoral students.

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The present ecological crisis reflects a crisis in human consciousness, especially in the western world, where our relationship with the earth and cosmos has been largely shaped and influenced by the stories we have been told in our culture. The old stories, as manifested in the myths and world view...
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This thesis addresses issues of islandness and island identity in the fiction of Cape Breton's Alistair MacLeod and Newfoundland's Wayne Johnston. Through careful readings of their fiction, with supplementary evidence culled from biographical and secondary sources, the thesis shows that their work i...
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Cette étude qualitative comporte deux objectifs: 1) examiner les raisons qui motivent le choix d’un établissement postsecondaire chez sept finissants d’une école de langue française dans la région Évangéline à l’Île-du-Prince-Édouard; et 2) explorer l’expérience vécue par ces jeu...
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Potato farming and lobster fishing are two important industries on Prince Edward Island. However for both industries to be sustainable, they must be managed responsibly. Recently, agricultural runoff has been suspected to have caused numerous fish kills in rivers throughout the island. Although a pe...
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The host parasite system of the MSX parasite, Haplosporidium nelsoni, in the eastern oyster, Crassostrea virginica, poses many challenges for experimental study. The interactions that are involved in the development of the typically high prevalence and intensities of disease encountered in certain e...
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Natural products have long been recognized for their medicinal value in traditional medicine and remain an important component of modern drug discovery. Known for their immense structural diversity, natural products are secondary metabolites that often exhibit unique pharmacological properties. In t...
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In 2005, trichomonosis emerged as a new cause of substantial mortality in United Kingdom (UK) greenfinch (Carduelis chloris) and chaffinch (Fringella coelebs) populations. Similar to the UK, in the summer and fall of 2007–2009 and 2011, mortalities due to trichomonosis occurred in the Canadian Mar...
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Effective control of parasitic sea lice (including Lepeophtheirus salmonis and Caligus elongatus), is a major challenge currently facing sea cage salmon aquaculture. Emamectin benzoate (EMB; SLICE®), a macrocyclic lactone (ML), has been the drug of choice for sea lice treatment over the past decade...
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The United Nations Convention on the Law of the Sea (UNCLOS) contained a specific section for “Archipelagic States” (Part IV) which are given many rights under the archipelagic regime including, if desired, to designate archipelagic sea lanes (ASLs) through their archipelagic waters. While desig...
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This thesis brings together the study of islands, anthropology, and postcolonialism; it discusses (1) how global assemblages, such as colonial interactions and neoliberal economies influence individual well-being and local health care ontologies as practice on islands, and (2) the space and place of...
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This thesis reviews the development and use of watermills from antiquity to the present, including the economic, environmental and social significance of milling during this time. More specifically, it explores the rise and fall of water-powered technology on two small islands with quite different w...
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Alcyonacean octocorals (Order Alcyonacea, amended from Order, Gorgoniidae) are both dominant on Caribbean reefs and prolific sources of bioactive natural products. Although extensive literature has been published with respect to stony coral-associated bacteria, very little is known regarding bacteri...
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SOXC transcription factors are key transcriptional regulators that have been shown to control self-renewal and differentiation in tissues during development in vivo, but have not been studied in the mammalian kidney. Our lab has previously demonstrated that all three members of the SoxC genes family...
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The field of fungal taxonomy has been enduring in recent years due to the progress and application of molecular tools used in concert with morphological analysis. The fungal kingdom is extremely diverse and estimated to include 1.5 million species. Only 11% of these fungi are currently described in ...
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In controlled release, each patient’s body displays different pharmacokinetics for the degradation of the drug delivery system affecting the release of the bioactive compound. The proposed research aims to develop polymeric systems based on a host/guest core capable of indicating controlled releas...
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Obesity has become an increasingly common health condition over the last several decades. It has been estimated that this largely preventable disease affects over one billion people worldwide and that its prevalence will have doubled by the year 2030. Currently, obesity is the leading cause of preve...
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BACKGROUND Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy (HCM). Human patients with HCM have high serum concentrations of biomarkers of collagen synthesis, indicating a profibrotic state. This abnormality exists in sarcomere mutation carriers both with and without overt left ventr...
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Marine invertebrates, including octocorals, are a prolific source of marine natural products (MNPs) and are also known to host diverse microbial communities. It is well-established that marine microbes are producers of bioactive secondary metabolites. Accordingly, it is hypothesized that bioactive m...
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The American lobster (Homarus americanus) is harvested along the eastern seaboard of North America and forms the economic backbone of many small fishing communities in Atlantic Canada and the northeastern United States. The industry sets minimum size (carapace length) for harvesting American lobster...
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The American lobster (Homarus americanus) is the most economically significant commercial fishery species in Canada. The Canadian lobster fishery provides tens of thousands of jobs, and is the economic driver of hundreds of rural communities in Atlantic Canada and Quebec. The adult lobster is suscep...
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Schizophrenia is a devastating neurological disorder that affects approximately 1% of the population and is characterized by positive, negative, and/or cognitive symptoms. Positive symptoms are associated with increased glutamate (Glu) and/or dopamine (DA) signaling in the nucleus accumbens (NAcc) w...
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The purpose of this study is to describe the geographic distribution of Aboriginal people who live in remote, isolated Aboriginal communities in Canada in terms of how geographic settings and features, particularly those that are characteristic of island dwellers, are related to and can impact aspec...
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The emergence of Caribbean small island states (SIS) through the 'demonstration effect‘ has resulted in even some of the smallest Caribbean islands achieving sovereignty. Past conventional security threats, such as the 1983 coup and intervention in Grenada, have resulted in the US Commonwealth Car...
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Sturgeon are harvested worldwide for their meat and eggs, sold as caviar and are among the most economically important fish species worldwide. A generally low physiological response to external stimuli/stressors has been documented in these phylogenetically primitive species. Considering how little ...
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Allergic diseases are a major medical concern with increasing prevalence in the world. Inflammation is one of the hallmarks of allergic diseases. Long chain n-3 polyunsaturated fatty acids (PUFAs) have been shown to inhibit allergic inflammation, but their direct effect on activation of the mast cel...