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Regulation of the matrix metalloproteinases (MMPs), the major mediators of extracellular matrix (ECM) degradation, is crucial to regulate ECM proteolysis, which is important in metastasis. This study examined the effects of 3 flavonoid-enriched fractions (a crude fraction, an anthocyanin-enriched fr...
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The development of obesity and associated insulin resistance involves a multitude of gene products, including proteins involved in lipid synthesis and oxidation, thermogenesis, and cell differentiation. The genes encoding these proteins are in essence the blueprints that we have inherited from our p...
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PURPOSE: To determine whether neonatal abstinence scores of infants exposed to methadone in utero differed by infant feeding method. DESIGN: A retrospective chart review. SUBJECTS: Twenty-eight term infants that were exposed to methadone in utero and exhibited symptoms of neonatal abstinence syndr...
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Purpose: This study explored the experiences of NICU nurses in caring for infants with neonatal abstinence syndrome (NAS). Design: A qualitative research approach was used with open-ended questions employing computer-assisted personal interviews. Sample: Fourteen NICU nurses employed in a regional...
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Multiple Sclerosis (MS) is an autoimmune disorder of the central nervous system. The average onset of the disease is 30 years of age, and it afflicts women more often than men (ratio of approximately 2:1). The symptoms of the disease include fatigue, motor weakness, heat sensitivity, reduced mobilit...
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We conducted in-class written surveys of fourht to eighth grade children's eating and smoking behaviours in southwestern Ontario (n=870) and Charlottetown (n=423) in order to facilitate local school boards' and health units' planning of health education initiatives. Using chi-square a...
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This review describes the mechanisms by which polyunsaturated fatty acids regulate the activity of the nuclear transcription factors, peroxisome proliferator-activated receptor and sterol regulatory element binding protein-1, and it describes the role that the peroxisome proliferator-activated recep...
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A needs assessment was conducted to explore the educational interests of 28 residents of a retirement community in the Niagara region of Ontario. Most were interested in education for leisure and personal development, specifically related to health maintenance and quality of life. (JOW)
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Background: Wizards of Motion is a program of curriculum delivery through which experts in Kinesiology introduce grade 7 students to applications of physics for human movement. The program is linked closely to Ministry of Education curriculum requirements but includes human movement applications and...
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Despite growing interest in the biomechanical mechanisms of sports-related concussion, ice hockey and the youth sport population has not been studied extensively. The purpose of this pilot study was: 1) to describe the biomechanical measures of head impacts in youth minor ice hockey players; and, 2)...
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The significance of the Internet, as a tool for health researchers has yet to be determined. Although search engines have been developed to use the Internet in health database information retrieval, the current practice is for health researchers to use the Internet as a billboard to post facts and i...
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Describes the development of an electronic curriculum in two undergraduate courses in quantitative methods and Epidemiology. Examines an underlying theoretical framework upon which the development of the Internet components was based. (Contains 20 references.) (DDR)
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Taurine status and pregnancy outcome were assessed in rats fed low dietary taurine and varying doses of guanidinoethyl sulfonate (GES), a structural analogue of taurine. Female Sprague–Dawley rats (225–270 g) were mated overnight and assigned to one of four groups from day 0 to 20 of gestation...