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During metamorphosis, the tadpole neuroendocrine brain is a major target for the organisational effects of hormones acting via both endocrine feedback mechanisms and local hormone production. While the receptor-mediated actions of thyroid hormones in brain development have been well described, there...
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The Gulf of St. Lawrence aster, Symphyotrichum laurentianum (Fernald) G.L. Nesom (Asteraceae), a small annual halophyte endemic to disturbed and highly transient habitats in the Gulf of St. Lawrence, is classified as "threatened" by the Committee on the Status of Endangered Wildlife in Canada. Lepid...
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Blue mussel Mytilus edulis aquaculture lines and associated gear provide habitat for sessile and mobile epifaunal fouling organisms. Due to food limitations and substrate space, these species are likely to interact among themselves and with mussels. In some areas of Prince Edward Island and elsewher...
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Two agricultural runoff events involving the pesticide azinphos-methyl occurred in July 2002 on the Wilmot River, Prince Edward Island, Canada, resulting in the death of thousands of fish. The fish communities from three sites on this river had been sampled in 2001, permitting comparisons of brook t...
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Regulation of the matrix metalloproteinases (MMPs) is crucial to regulate extracellular matrix (ECM) proteolysis which is important in metastasis. This study investigated the mechanism(s) by which three flavonoid-enriched fractions from lowbush blueberry (Vaccinium angustifolium) down-regulate MMP a...
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Several lines of evidence suggest that L-type Ca2+ channels (1,4-dihydropyridine receptors) are modulated by GTP-binding proteins. We have further examined this interaction by measuring the effect of 1,4-dihydropyridines on GTPase activity in brain membranes. Dihydropyridine agonists significantly i...
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Rana pipiens and R. clamitans were evaluated during 1993-94 at 8 wetland sites in Ontario, Canada, 4 of which were within apple orchards, to determine if environmental changes associated with orchard management affected measured biological parameters. Size, age, genetic variation, condition indices,...
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Oncostatin M (OSM) is a growth and differentiation factor which has been shown to exert both stimulatory and inhibitory effects on tissue invasion in various cell lines. Tissue invasion is a key marker of metastases and can be monitored by examining activities associated with ECM degradation such as...
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In the present study, the expression and the regulation of ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC) was examined in a series of oncogene transformed cell lines. The expression of both ODC and SAMDC was found to correlate with the nature of the oncogene expressed a...
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We compared a range of anatomical features of northern leopard frogs (Rana pipiens Schreber) collected from areas where deformity rates were low (-2% in nonstressed regions) and high (-40% in the stressed region) to determine if one or more of these characters might be useful in detecting developmen...
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Small mammal communities were studied in eight vegetation types of the Prince Edward Island National Park. Ten species were trapped. Shannon-Weiner index of diversity was high in Red Pine[Pinus resinosa] plantations (1.33 and 1.55) and a bog (1.47), and low for opened habitats such as a dune (0.19),...
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We compared the nucleosomal organization, histone H1 subtypes, and histone H1 phosphorylated isoforms of ras-transformed and parental 10T1/2 mouse fibroblasts. In agreement with previous studies, we found that ras-transformed mouse fibroblasts have a less condensed chromatin structure than normal fi...
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Natural 'bioactive' factors have the ability to attenuate atherogenesis in in vitro and in vivo models. The effects of cranberry on the expression of two inflammation-linked enzymes, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), were examined in aortic smooth muscle ...
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The preceding review indicates that there is convincing evidence for the presence of adenosine in and release of adenosine from capsaicin-sensitive small diameter primary afferent neurons in the spinal cord (Fig. 1). Within the dorsal spinal cord, adenosine inhibits the transmission of nociceptive i...
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The relative importance of predatory decapod crustaceans in sedimentary communities depends on the spatial variability in their abundance and composition. At the scale of a fjord, such spatial patterns could be related to sill-mediated larval supply. This study examines larval and adult distribution...
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Aim The aim of this study was to investigate the effects of climate, geography, census area and the distribution of body mass on the mass : density relationship in terrestrial mammal populations. Location The areas covered include most major terrestrial biomes including the tropics, savannas, and te...
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The effect of 7 juvenile hormone analogues on the development of larvae of Choristoneura fumiferana was studied in the laboratory at 23 degrees C, LD 16:8 and 65% RH by topical application of the compounds to early 6th-instar larvae. Fenoxycarb showed the highest potential for control, with an LC50 ...