Oncostatin M (OM) is a member of the interleukin-6 (IL-6) cytokine subfamily. The binding of OM to its receptor initiates signal transduction through JAK-signal transducers and activators of transcription (STAT) pathways and activates transcription activators through mitogen-activated protein (MAP) ...

Epidemic mortalities of chinook salmon alevins (Oncorhynchus tshawytscha) have occurred annually at a freshwater hatchery at the Chehalis River, British Columbia, Canada, since 1982. Previous work has identified branchial epithelial hyperplasia as the predominant pathological change. Our initial wor...

For 3 weeks, 128 male Sprague-Dawley rats, 3 weeks old, were fed on diets containing no protein, casein, soyabean meal, roasted or raw soyabeans, or sweet white lupin (Lupinus albus) cultivar Primorski or Ultra without or with 0.1% lysine or 0.2% methionine. Relative net protein ratio (RNPR) (casein...

Programmed cell death and apoptosis have now been recognised as biological phenomena which are of fundamental importance to the integrity of organisms. What may have evolved as an altruistic defence against pathogen invasion in simple organisms is now a major regulatory mechanism in the development ...

The objective ofthis study was to evaluate the efficacy of intramammary tilmicosin, administered at drying-off, for eliminating Staphylococcus aureus infection, and to identify risk factors for S. aureus cure during the dry period. A total of 219 naturally infected cows, representing 308 quarters, w...

Termination of pregnancy (abortion) was successful in four of four bitches that received PGF(2)alpha (125 mug/kg bid s.c.) and in two or four bitches that received bromocryptine (62.5 mug/kg bid po) for up to 6 d beginning 43 to 45 d post ovulation. Four sham-treated controls whelped normally at ter...

An investigation into bacterial water quality problems was conducted on an interconnected stream and irrigation system within the Oldman River Basin of southern Alberta, Canada. Levels of indicator bacteria, including fecal coliforms, generic Escherichia coli and fecal streptococci, were repeatedly ...

A study comparing invasive versus oscillometric techniques for the measurement of arterial blood pressure was carried out in 4 anaesthetised sows undergoing laparoscopy. Regression analysis was used to determine the correlation coefficient. Bias was 19.2 for systolic, 20.6 for mean and 18.8 for dias...

This study evaluated the sensitivity, specificity and positive predictive value/negative predictive value of the CITE ELISA, the first version of the SNAP ELISA, and the revised version of the SNAP ELISA (SNAP ELISA 1 and SNAP ELISA 2, respectively). This study also evaluated a non-commercial versio...

A fistula of the parotid salivary duct is an abnormal communication between the duct and the skin, resulting in the drainage of saliva to the exterior. Fistulas of the parotid gland or duct are usually due to trauma but may be idiopathic (Pascoe 1999); they are known to occur in human beings, dogs a...

In 1992, the porcine reproductive and respiratory syndrome virus (PRRSV) of European type (PRRSV-EU) was introduced in Denmark. By 1996, the virus had spread to approximately 25% of the Danish herds. In January 1996, a modified-live vaccine based on the American type of the virus (PRRSV-US) was used...

Infectious salmon anemia (ISA) is a viral disease occurring in farmed Atlantic salmon (Salmo salar) that is characterized by lethargy, anorexia, anemia and death. To control the disease in New Brunswick, Canada, 7.5 million fish from outbreak cages have been destroyed since 1997. Despite changes mad...

An acute onset of illness was reported in a lactating dairy herd in Canada in which monensin had been incorporated in error in its ration at almost 10 times the prescribed level. All of the lactating cows became lethargic, were inappetant, developed diarrhea, and had decreased milk production from 2...

A computerized health and production information network (APHIN: Animal Productivity and Health Information Network) was developed in Prince Edward Island (P.E.I.) to serve the livestock industries. The dairy portion of the network is designed primarily to aid in the reduction of the unit cost of pr...