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A laboratory quality assurance (QA) program can minimize errors and provide confidence in the validity of laboratory test results. The structure of a QA program varies somewhat among laboratories but usually requires addressing a QA manual, QA goals, quality of resources, standard operating procedur...
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A malignant neoplastic process originating from gall bladder epithelium was diagnosed in a 14-year-old, spayed female, domestic shorthair cat. The tumor produced widespread pulmonary and lymphatic metastases. The clinical and pathological manifestations are described. Neoplasia arising from the gall...
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The complexity and uncertainty of diagnostic information makes the diagnostic process difficult to learn, teach, and practice. Fuzzy logic methods, used successfully with complex industrial control problems, may be appropriate to model the range of uncertainties found in medical diagnostic informati...
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A computer-based fuzzy systems approach to diagnosis was compared with a standard rule-based approach for ability to diagnose 1 or more of 14 diseases in postpartum cows. A comparison between the 2 systems, using the same 12 input variables (clinical signs and laboratory measurements), resulted in 9...
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This study was carried out to determine the diagnostic usefulness of postmortem eyefluid analysis in estimating antemortem concentrations of serochemical constituents. A total of 31 cattle, 18 dogs and 22 cats were selected from routine elective euthanasia submissions to a diagnostic laboratory. For...
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Various hypotheses have been proposed for the pathogenesis of the neurological signs associated with bovine enteric coccidiosis. We undertook a prospective study of cases of bovine enteric coccidiosis with and without nervous signs to test the validity of these hypotheses and explore other possible ...
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Reported are the results of preliminary attempts to characterize the molecular weight, heat sensitivity and other features of a labile neurotoxin identified in the serum of calves exhibiting neurological signs in association with coccidial enteritis. The labile neurotoxin activity is heat labile (60...
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Mouse inoculation was used to test for the presence of a toxin in the serum, cerebrospinal fluid, and intestinal contents collected from cases of bovine enteric coccidiosis, with and without neurological signs, and from control calves. Intravenous inoculation of mice with 10 mL/kg of serum from calv...
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In order to test the hypothesis that treatment with glucocorticoids causes pancreatitis in dogs, 18 mongrel dogs were divided into three groups of six individuals, each group receiving prednisone at different doses orally or intramuscularly for two weeks. Two groups consisting of six dogs each serve...
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Glucocorticoid treatment in dogs is known to cause hepatocellular swelling due to accumulation of cytoplasmic compounds which variably have been identified histochemically as fat, glycogen, or water. In the present study changes in dog liver, after treatment for 15 days with two different doses of o...
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Enterotoxigenic colibacillosis was experimentally produced in four colostrum-deprived calves given 10(10) Escherichia coli strain 210 (serotype 09+:K30+:K99-:F41-:H-) orally and the histopathological changes compared to those seen in colostrum-fed calves infected in an earlier study with strain B44 ...
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A study was undertaken to determine the blood chemical variables and compare changes that occurred with ruptured bladders and ruptured urethras in steers and yearling bulls. The fatality rates were 10.5% in steers with ruptured urethras and 50.8% in steers with ruptured bladders. Both groups had sig...
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Electrolyte and urea levels of vitreous humor collected from bovine eyes at various times postmortem, were compared with serum levels in the same animals. Provided the vitreous humor was filtered immediately after collection, measured levels of total calcium (Ca), potassium ions (K+), sodium ions (N...
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Predisposing causes of bovine post-parturient hemoglobinuria are summarized along with suspected pathogeneses, clinical signs, laboratory findings, clinical management and early experimentation.
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Two methods for detecting feline leukaemia virus (FeLV) antigen in peripheral blood were compared in 128 cats: immunofluorescence assay (IF) and an enzyme-linked immunosorbent assay (ELISA). Both healthy cats and cats with a variety of diseases, including lymphosarcoma and myeloproliferative disorde...
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The microhematocrit heat-precipitation methods of Millar et al (1971) and Schalm et al (1975) were compared with the reference clottable protein method of Ratnoff and Menzie (1951) in the measurement of plasma fibrinogen concentration in horses. The millar et al method was more precise and accurate ...
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A rapid radioimmunoassay method for detecting plasma cortisol was evaluated and the results found to be accurate, precise and reproducible. Sample storage and preparation were examined; refrigeration and delayed serum separation decreased the cortisol concentration but freezing for up to six months ...
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Intestinal loops, ligated in colostrum-deprived calves were used to compare the virulence of four isolates of bovine rotavirus. Histopathological studies were carried out on infected and control loops and measurements of villous length, crypt depth, villus:crypt ratio and crypt mitotic index were re...