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Stability-indicative detn. of bambuterol hydrochloride (BH) in the presence of its degrdn. product (terbutaline), which is also the metabolite, is investigated. The degrdn. product was isolated, via acid-degrdn., characterized and elucidated. Selective quantification of BH, singly in bulk form, phar...
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Order of proceedings for the installation ceremony and a biographical sketch of Dr. Abd-El-Aziz.
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The present study demonstrates the benefits of combinatorial antioxidant therapy in the treatment of ischemic stroke. Male Sprague-Dawley rats were anaesthetised and the middle cerebral artery (MCA) was occluded for 30 minutes followed by 5.5 hours of reperfusion. Pretreatment with resveratrol 30 mi...
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Edaravone, an electron spin trapper with radical scavenging activity, has been shown to be effective in reducing infarct volume in humans following ischemic stroke. However, concerns of edaravone-induced renal toxicity have limited its clinical adoption. Previous work has demonstrated that edaravone...
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The reaction of dichloro-terminated organoiron complex [Fe(1,4-C6H4Cl2)Cp]+PF6- (3) with 4-hydroxybenzoic acid resulted in the formation of dicarboxylic acid organoiron complex 4. 4′-Hexyl alcohol-2,2′:6′,2″-terpyridine (hextpy) 2 was reacted with dicarboxylic acid organoiron complex 4 or th...
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Cyclic aryl ethers, thioethers or amines, and methods for synthesis are
disclosed. These cyclic aryl compounds are synthesized by combining a first
dinucleophile with a substituted benzene metallized electron-withdrawing
complex,
having halo or nitro substituent groups, to form a li...
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Cyclic aryl ethers, thioethers or amines, and methods for synthesis are disclosed. These cyclic aryl compounds are synthesized by combining a first dinucleophile with a substituted benzene metallized electron-withdrawing complex, having halo or nitro substituent groups, to form a linear bimetallized...
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Multifunctional macromolecules continue to attract attention. Here, three generations of a new family of bifunctional organoiron dendrimers are reported, which are synthesized from a redox-active organoiron complex, η6-dichlorobenzene-η5-cyclopentadienyl-iron(II). The facile chemistry of the compl...
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Sandwich complexes-containing polymers are attractive complements of organic-based polymers as the former feature intriguing properties. These include excellent thermal stability, redox activity, magnetic, electrical, and optical properties. This review surveys many of the synthetic approaches that ...
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A novel series of functionalized thiophenes incorporating coumarin, pyrene and naphthalene pendants were synthesized by Steglich esterification in the presence of DCC/DMAP (dicyclohexylcarbodiimide/N,N-dimethylaminopyridine) and the synthesized monomers were electrochemically deposited onto glassy c...
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A novel series of thiophenes with terpyridine pendant groups were synthesized by Steglich esterification in the presence of DCC/DMAP and the synthesized monomers were electrochemically polymerized onto microelectrodes using glassy carbon and carbon fiber as active electrode materials. Each pendant g...
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Previous work in our laboratory demonstrated the utility of synthetic combinations of two naturally occurring, biologically active compounds. In particular, we combined two known anti-oxidant compounds, lipoic acid and apocynin, covalently linked via an ester bond (named UPEI-100). In an animal mode...
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This thesis describes the synthetic strategies for the incorporation of a number of metal species into a series of polynorbornenes, as well as their characterization and thermal analysis. This was accomplished through the synthesis of new monometallic norbornene compounds containing chromium and iro...
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