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Milbemycin oxime was used to treat dogs with natural infections of the fox lungworm, Crenosoma vulpis and the French heartworm, Angiostrongylus vasorum. Crenosomosis was identified in 42 of 202 dogs with clinical signs of coughing, dyspnoea or exercise intolerance by a Baermann analysis of faecal sa...
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By cross hybridization with the mammalian growth-related protein, GAP-43, we have isolated several Drosophila cDNAs and genomic sequences. These sequences correspond to a single copy gene that encodes two developmentally regulated transcripts 2.4 and 2.0 kb in length. The predicted protein sequence ...
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Crenosoma vulpis is a metastrongylid lungworm of canids causing chronic respiratory disease in dogs in parts of North America and Europe. The objective of this study was to determine the efficacy of imidacloprid 10% + moxidectin 2.5% (Advantage Multi/Advocate Topical Solution) against C. vulpis infe...
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Sheep experimentally infected with Fascioloides magna were used in a controlled study to determine the flukicide activity of different doses of albendazole (methyl [5(propylthio)-1H-benzimidazol-2-yl] carbamate). Sheep, about 4 months old, were inoculated with 100 metacercariae of F magna and treate...
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The hematologic and clinico-pathologic response to Fascioloides magna infection in cattle and guinea pigs was investigated. Twelve calves (six infected and six controls) were monitored for 26 weeks after inoculation with 1000 metacercariae. All calves remained healthy and there were no significant d...
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The long-term (i.e., 4-5 months) effects of large doses (3 X 50 mg/kg) of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine-containing afferents were studied in the NMRI strain of mice. Recently improved in vivo electrochemical methods were first used to examine the magnitude,...
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Helminth parasite infection of the canine and feline respiratory tract is uncommon in North America. This article reviews the prevalence, etiology, diagnosis, and treatment of helminth parasite infections in dogs and cats. The diagnosis of parasitic infections caused by helminth parasites of the res...
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Angiostrongylus vasorum, French heartworm, is a metastrongloid parasite found in the pulmonary arteries and right ventricle of wild and domestic canids and various other animals. The natural definitive hosts are species of foxes. The geographic distribution of the parasite includes various countries...
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A young, female llama (Lama glama) was euthanized following the onset of hindleg paresis and paralysis. Live trematodes, identified as Fascioloides magna, were identified from the liver of this animal. This represents the first report of F. magna in a llama.
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This article is intended to be a practical guide to the identification of some platyhelminth, nematode, and acanthocephalan parasites found in aquatic freshwater turtles. A brief section on the treatment of these infections is provided..
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Cestodes are hermaphroditic flatworms (tapeworms) consisting of a scolex, neck region, and repeating segments. Cestodes lack a mouth, intestine, and body cavity. Life cycles are indirect, with the definitive host acquiring the adult form of the tapeworm by the ingestion of the larval metacestode sta...
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The guinea pig was used to study the pathology of Fascioloides magna, an important pathogen for sheep. Although flukes migrated freely through various tissues in infected guinea pigs, the most serious lesions occurred in the liver and lungs. The sequential development of lesions indicated that fluke...
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Crenosoma vulpis is a nematode lungworm that is highly prevalent in the red fox population of Atlantic Canada. Dogs are susceptible to infection with clinical signs consisting primarily of a chronic cough. A recent report of C. vulpis infection in 3 dogs on Prince Edward Island prompted an investiga...
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Larvae of Trichinella sp. were found in two of 208 red foxes (Vulpes vulpes) and one of 125 coyotes (Canis latrans) obtained from trappers from Prince Edward Island (Canada) in 1995 and 1996. A polymerase chain reaction based DNA biotyping method revealed the larvae to be isolates of Trichinella spi...
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The efficacy of closantel against experimentally induced Fascioloides magna infection in sheep was studied. In each of 3 experiments, closantel was administered 8 weeks after the sheep were given (oral inoculation) 100 metacercariae of F magna. In the 1st experiment, closantel was given orally to 5 ...
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In a study to evaluate the efficacy of clorsulon against Fascioloides magna infection in sheep, 12 ewes were inoculated orally with 100 metacercariae of F magna, and 6 were treated with clorsulon (15 mg/kg of body weight) 8 weeks after inoculation. The sheep were euthanatized 16 weeks after inoculat...
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A male and female silver fox (Vulpes vulpes) were diagnosed with naturally acquired infections of the lungworm Crenosoma vulpis at the Cherry Brook Zoo in St. John, New Brunswick, Canada. The main clinical sign was a chronic cough. Crenosomiasis was diagnosed by fecal examination using the Baermann ...
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Aquatic snails were collected at 148 sites from various wetland habitats in central Minnesota between May and September, 1988. Ten lymnaeid species were collected, including Lymnaea palustris, L. stagnalis, L. exilis, L. caperata, L. catascopium, L. megasoma, L. Fossaria modicella, L. (F.) parva, L....
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The pathophysiologic responses of 13 sheep inoculated orally with 100 metacercariae of Fascioloides magna were monitored for 4 months after inoculation. There were no differences in weight gains between these and a number of noninoculated control sheep throughout the experiment. Complete blood cell ...