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To test the acidifying ability of the distal portion of the nephrons in healthy dogs, 0.2 g of NH4Cl/kg of body weight was given PO. Samples for venous blood gas analysis and urine pH were taken hourly for 6 hours. Systemic acidemia developed, as evidenced by a statistically significant (P less than...
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The kinetic disposition and hemodynamic effects ot tetrandrine, l3 mg/kg i.v., over 30 s were studied in five anesthetized dogs during continuous monitoring of the ECG and systemic arterial pressure. Repeated determinations of cardiac output (CO) and pulmonary capillary wedge pressure (PCWP) were ma...
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Tumours of gastrin-secreting cells (gastinomas) which result in a characteristic clinical syndrome of hypergastinaemia, leading to gastric acid hypersecretion with subsequent severe gastrointestinal ulceration are reviewed. The most common clinical signs are anorexia, lethargy, weight loss, vomiting...
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Acidaemia stimulates renal ammonia production and excretion. This adaptive response allows increased H+ secretion and generation of new bicarbonate. To determine whether a relationship existed between urine ammonium (NH4+) concentration and excretion and urine anion gap (Na+ + K+ - Cl-), ammonium ch...
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This paper covers uncomplicated versus complicated infection, bacterial susceptibility and antibiotic selection, managing lower urinary tract infection and new approaches to chronic tract infection..
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Cell wall lipopolysaccharide (LPS) was identified as the receptor for the A. salmonicida bacteriophage strain 55R-1. Mutants of A. salmonicida resistant to phage 55R-1 were unable to adsorb phage 55R-1 and were shown to be defective in LPS structure. Purified A. salmonicida LPS inactivated phage 55R...
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The urine-blood carbon dioxide tension (PCO2) gradient was measured in 10 healthy mature Beagles after alkalinization of the urine by administration of sodium bicarbonate. The mean (+/- SD) urine-blood PCO2 gradient was 65.92 +/- 14.42 mm of Hg, with range of 38.2 to 82.2 mm of Hg. Mean urine PCO2 w...
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Lipopolysaccharides isolated from strains of Aeromonas hydrophila, virulent for fish and which autoaggregate during growth in static broth culture, were examined by sodium dodecyl sulphate-polyacrylamide gel electrophoresis. The lipopolysaccharides contained O-polysaccharide chains of homogeneous ch...
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The effect of enrofloxacin on the oral clearance and steady-state concentrations of digoxin in serum was evaluated in dogs. Digoxin was administered orally to six healthy adult Beagle dogs following a multiple-dose regimen of 0.0625 mg every 12 h for 23 days. From days 14 to 23 enrofloxacin was admi...
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Blood catecholamine levels were determined by high-performance liquid chromatography after placement of the cord around two teeth in a random sequence of the following treatments: (1) untreated cord to intact gingival crevice (C), (2) epinephrine cord to intact crevice (E1), and (3) epinephrine cord...
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A dog adopted as a stray in Spain and then brought to Canada 4 years prior to presentation was evaluated for polyarthritis. An electrophoresis showed a marked polyclonal gammopathy and synovial smears contained leishmanial organisms within macrophages.
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Methods for culling wild red deer (Cervus elaphus) were compared by observing behaviour and collecting post mortem samples from wild deer shot: (i) by a single stalker during daytime; (ii) by more than one stalker during daytime; (iii) by using a helicopter for the deployment of stalkers and carcase...
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Communication skills are considered a core clinical skill in human medicine. Recognizing the importance of communication skills and addressing them in veterinary curricula, however, is just beginning. In the fall of 2003, the Atlantic Veterinary College, University of Prince Edward Island, markedly ...
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A 1-year-old male Cairn Terrier was evaluated for chronic coughing that was aggravated by eating or drinking. Radiography revealed an esophageal diverticulum, regional megaesophagus, and focal interstitial densities in the right caudal and middle lung lobes. Using fluoroscopy and contrast radiograph...
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Five cases of hypoadrenocorticism in young related Nova Scotia duck tolling retrievers are discussed. Two were littermates and the others shared one or more common ancestors. No specific mode of inheritance was determined. Clinical and laboratory findings typical of hypoadrenocorticism were observed...
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To evaluate indices of renal function in healthy, growing Beagle puppies from 9 to 27 weeks of age and to determine whether indices change with age during this period. Animals-6 healthy Beagle puppies. PROCEDURE: Urine collections were performed at 2-week intervals in puppies 9 to 27 weeks old. Dail...
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A course book on presenting symptoms, and diseases of internal organs in dogs and cats. There is a self-assessment section containing 100 multiple-choice questions. Other titles in the same series have dealt with small animal surgery, cytology, pharmacology and toxicology..
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In a comparison of 2 formalin killed vaccines, SHAWOGEN using an isolate (AVC U-13220) of Vibrio anguillarum (serotype 2) isolated from cod, and a commercial vaccine (VIBROGEN-2) prepared from 3 isolates (2 V. anguillarum, and V. ordalii) the vaccines were given i.p. with mild anaesthesia, by sprayi...