Tumours of gastrin-secreting cells (gastinomas) which result in a characteristic clinical syndrome of hypergastinaemia, leading to gastric acid hypersecretion with subsequent severe gastrointestinal ulceration are reviewed. The most common clinical signs are anorexia, lethargy, weight loss, vomiting...

Acidaemia stimulates renal ammonia production and excretion. This adaptive response allows increased H+ secretion and generation of new bicarbonate. To determine whether a relationship existed between urine ammonium (NH4+) concentration and excretion and urine anion gap (Na+ + K+ - Cl-), ammonium ch...

This paper covers uncomplicated versus complicated infection, bacterial susceptibility and antibiotic selection, managing lower urinary tract infection and new approaches to chronic tract infection..

Cell wall lipopolysaccharide (LPS) was identified as the receptor for the A. salmonicida bacteriophage strain 55R-1. Mutants of A. salmonicida resistant to phage 55R-1 were unable to adsorb phage 55R-1 and were shown to be defective in LPS structure. Purified A. salmonicida LPS inactivated phage 55R...

The urine-blood carbon dioxide tension (PCO2) gradient was measured in 10 healthy mature Beagles after alkalinization of the urine by administration of sodium bicarbonate. The mean (+/- SD) urine-blood PCO2 gradient was 65.92 +/- 14.42 mm of Hg, with range of 38.2 to 82.2 mm of Hg. Mean urine PCO2 w...

Lipopolysaccharides isolated from strains of Aeromonas hydrophila, virulent for fish and which autoaggregate during growth in static broth culture, were examined by sodium dodecyl sulphate-polyacrylamide gel electrophoresis. The lipopolysaccharides contained O-polysaccharide chains of homogeneous ch...

The effect of enrofloxacin on the oral clearance and steady-state concentrations of digoxin in serum was evaluated in dogs. Digoxin was administered orally to six healthy adult Beagle dogs following a multiple-dose regimen of 0.0625 mg every 12 h for 23 days. From days 14 to 23 enrofloxacin was admi...

Blood catecholamine levels were determined by high-performance liquid chromatography after placement of the cord around two teeth in a random sequence of the following treatments: (1) untreated cord to intact gingival crevice (C), (2) epinephrine cord to intact crevice (E1), and (3) epinephrine cord...