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OBJECTIVE: To evaluate alterations in lymphocyte subpopulations, CBC results, and clinical signs in neonatal calves inoculated with 3 commercially available proprietary multiple-antigen vaccines containing known quantities of endotoxin. DESIGN: Prospective, randomized controlled field trial. ANIMA...
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The extent of the serological cross-reactivity was determined in the indirect fluorescent antibody (IFA) test for B. gibsoni, and the optimal cut-off titre for seropositivity. The lowest titre to B. gibsoni detected in a dog with naturally acquired clinical babesiosis was 1280 and 7 of 12 dogs had t...
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OBJECTIVE: To determine whether treating cows with antimicrobials at the end of lactation would lower the incidence of clinical mastitis, improve milk production, and decrease somatic cell count (SCC) in the subsequent lactation. DESIGN: Randomized blind field trial. ANIMALS: 233 Holstein cows fr...
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In studies between March and July 1987, toxigenic type D P. multocida was isolated from the nasal cavities of pigs in one (2%) of 50 randomly selected herds. Toxigenic isolates were also recovered from 2 (8%) of a separate group of 25 herds that had purchased pigs from a known infected piggery in So...
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Sera (n = 806) from 50 populations of bighorn sheep (O. canadensis) in California, USA, were evaluated for antibodies to Psoroptes sp. mites using a kinetic ELISA. Test values for each sample were determined to be either positive or negative at each of 2 ELISA cutoff values that provided either 100%...
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For 3 California, USA, dairy herds with bulk tank somatic cell counts <200 000/ml, twice daily milking and no mastitis vaccine, 254 quarters with mild clinical mastitis were randomly assigned to 3 groups. Group A (n = 74) was treated with 62.5 mg of intramammary amoxicillin every 12 h for 3 milkings...
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During 1986 and 1987, mortality, morbidity, case-fatality, and culling rates were estimated for endemic disease conditions in 43 randomly selected California dairy farms. Data were collected mainly by farmer interview. Age-specific mortality rates were: calves 22.8 per 1000 calf-months at risk; youn...
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In a field trial at a commercial piggery 22 pigs were vaccinated intraperitoneally, at 30 days and 60 days old, with formalin-killed M. pneumoniae plus adjuvant. Two other groups of the same size, one receiving a ration containing antibiotics, were not vaccinated. The mean ELISA ratio of the vaccina...
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Objective: To define scintigraphic, physical examination, and scapular ultrasonographic findings consistent with bone fragility syndrome (BFS) in horses; develop indices of BFS severity; and assess accuracy of physical examination, scapular ultrasonography, and serum biomarkers for BFS diagnosis. De...
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Weaning, particularly the widespread practice of abrupt separation of the mare and foal, has been shown to be a stressful event for horses. Physiological changes in foals measured after weaning include increased blood cortisol concentrations and a subsequent decrease in cell-mediated immune response...
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REASONS FOR PERFORMING STUDY: African horse sickness is an insect-transmitted, noncontagious disease of equids caused by African horse sickness virus (AHSV). Mortality can exceed 90% in fully susceptible horse populations. A live-attenuated (modified live) cell-culture-adapted (MLV) polyvalent AHSV...
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Blood samples collected from 503 suspect cases of African horse sickness (AHS) and another 503 from uninfected, unvaccinated South African horses, as well as 98 samples from horses from an AHS free country, were tested with an AHS virus (AHSV) specific duplex real-time reverse transcription quantita...
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Objectives: To estimate likelihood ratios (LRs) of correctly identifying internal Corynebacterium pseudotuberculosis infection in horses by measurement of antibody titers via serum synergistic hemolysis inhibition (SHI) testing. Design: Retrospective case-control study. Animals: 170 horses (171 reco...
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Identification of risk factors for subclinical intramammary infections (IMI) in dairy goats should contribute to improved udder health. Intramammary infection may be diagnosed by bacteriological culture or by somatic cell count (SCC) of a milk sample. Both bacteriological culture and SCC are imperfe...
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Objective: To estimate the prevalence of radiographic abnormalities (lesions) in Thoroughbred racehorses at 2-year-old in-training sales and determine whether these lesions and 1-furlong presale workout times were associated with subsequent racing performance. Design: Retrospective cohort study. Ani...
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Reasons for performing study: Identification of exercise history patterns that are related to catastrophic scapular fracture will facilitate prevention of racehorse fatalities. Objectives: To determine if exercise patterns are associated with scapular fracture in Thoroughbred (TB) and Quarter Hors...
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Diagnostic strategies to detect Mycobacterium avium subsp. paratuberculosis (MAP) super-shedder cows in dairy herds have been minimally studied. The objective of the current study was to compare the cost-effectiveness of strategies for identification of MAP super-shedders on a California dairy herd ...
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Cheetahs (Acinonyx jubatus) are a highly threatened species because of habitat loss, human conflict, and high prevalence of disease in captivity. An epidemic of feline infectious peritonitis and concern for spread of infectious disease resulted in decreased movement of cheetahs between U.S. zoologic...
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Salmonella is one of the most common foodborne pathogens associated with diarrheal disease in humans. Food animals, especially poultry, are important direct and indirect sources of human salmonellosis, and antimicrobial resistance is an emerging problem of public health concern. The use of antimicro...
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Objective--To evaluate associations between Mycobacterium avium subsp paratuberculo-sis (MAP) and caudal fold tuberculin (CFT) test results in cattle. Design--Longitudinal and cross-sectional evaluations. Animals--1 California (approx 3,600 cows) and 3 Colorado (approx 640, 1,190, and 1,480 cows) da...
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Background Aleutian mink disease virus (AMDV) is the cause of a chronic immune complex disease, Aleutian disease (AD), which is common in mink-producing countries. In 2005, implementation of an AMDV eradication programme in Finland created a need for an automated high-throughput assay. The aim of th...
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Real-time quantitative polymerase chain reaction (qPCR) testing for Mycobacterium avium subspecies paratuberculosis (MAP) in fecal samples is a rapid alternative to culture on Herrold egg yolk medium (HEYM), the traditional antemortem reference test for MAP. Although the sensitivity and specificity ...
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