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OBJECTIVE: To determine the effects of medetomidine, administered i.v., on serum insulin and plasma glucose concentrations in clinically normal dogs. ANIMALS: 6 healthy adult Beagles. PROCEDURE: Dogs were randomly assigned to each of 3 treatments in a prospective cross-over study design. Serum insul...
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A course book on presenting symptoms, and diseases of internal organs in dogs and cats. There is a self-assessment section containing 100 multiple-choice questions. Other titles in the same series have dealt with small animal surgery, cytology, pharmacology and toxicology..
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BACKGROUND Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy (HCM). Human patients with HCM have high serum concentrations of biomarkers of collagen synthesis, indicating a profibrotic state. This abnormality exists in sarcomere mutation carriers both with and without overt left ventr...
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OBJECTIVE: To determine whether phenobarbital treatment of epileptic dogs alters serum thyroxine (T4) and thyroid-stimulating hormone (TSH) concentrations. DESIGN: Cross-sectional study. ANIMALS: 78 epileptic dogs receiving phenobarbital (group 1) and 48 untreated epileptic dogs (group 2). PROCEDURE...
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A multicentric prospective study was conducted to monitor the effect of phenobarbital on serum total thyroxine (T4) and thyroid-stimulating hormone (TSH) concentrations in epileptic dogs. Serum T4 concentrations were determined for 22 epileptic dogs prior to initiation of phenobarbital therapy (time...
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Phenobarbital (PB) therapy is frequently associated with elevated serum alanine aminotransferase (ALT) and alkaline phosphatase (AP) activities in dogs without clinical signs of liver disease. The goal of this study was to determine if increased serum ALT and AP activities in clinically healthy PB-t...