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The objective of this study was to investigate whether zinc interacts with taurine to influence the development of the electroretinogram. Virgin female Sprague-Dawley rats were bred overnight and assigned to 1 of 4 treatments in a 2 × 2 factorial design with two levels of zinc (50 μg/g through ges...
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Taurine status and pregnancy outcome were assessed in rats fed low dietary taurine and varying doses of guanidinoethyl sulfonate (GES), a structural analogue of taurine. Female Sprague–Dawley rats (225–270 g) were mated overnight and assigned to one of four groups from day 0 to 20 of gestation...
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Presents a study which investigated whether zinc interacts with taurine to influence the development of retinal structure and function, using virgin female Sprague-Dawley rats. Materials and methodology of study; What the histological examination of the retinas from rats deficient in zinc and taurin...
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Diets rich in fruits and vegetables have been shown to improve patient prognosis in a variety of cancers, a benefit partly derived from phytochemicals, many of which target cell death pathways in tumor cells. Cranberries (Vaccinium macrocarpon) are a phytochemical-rich fruit containing a variety of ...
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Prostate cancer is one of the most common cancers in the world, and its prevalence is expected to increase appreciably in the coming decades. As such, more research is necessary to understand the etiology, progression and possible preventative measures to delay or to stop the development of this dis...
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Beneficial health effects of cranberries (CBs) and wild blueberries (BBs), such as reduced levels of oxidative stress, have been demonstrated in feeding studies. These Vaccinium berries contain high levels of flavonoids; however, the bioavailability of flavonoids is generally low. We investigated th...
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Purpose: To assess adults' knowledge of dietary recommendations, food sources of key nutrients, food choices, and diet-disease relationships. Methods: A previously validated survey, designed to assess nutrition knowledge, was adapted for use in Prince Edward Island and mailed to a random sample of 3...
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The spontaneously hypertensive stroke-prone (SHRSP) rat is a commonly used model of cerebrovascular disease and hypertension. SHRSP rats have been shown to develop stroke-related symptoms (SRS) by age 14 weeks when fed a purified diet, such as AIN-93G, supplemented with 1% NaCl. We conducted a patho...
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Feeding flavonoid-rich blueberries to spontaneously hypertensive stroke-prone rats (SHRSP) lowers blood pressure. To determine whether this is due to inhibition of angiotensin-converting enzyme (ACE) activity, as seen with other flavanoid-rich foods, we fed blueberries to SHRSP and normotensive rats...
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Regulation of the matrix metalloproteinases (MMPs) is crucial to regulate extracellular matrix (ECM) proteolysis which is important in metastasis. This study investigated the mechanism(s) by which three flavonoid-enriched fractions from lowbush blueberry (Vaccinium angustifolium) down-regulate MMP a...
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Oxidative stress is an important element in the etiology of ischemic stroke. Lowbush blueberries (Vaccinium angustifolium Aiton) have a high antioxidant capacity and thus we determined whether consumption of lowbush blueberries would protect neurons from stroke-induced damage. Rats were fed AIN-93G ...
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Regulation of the matrix metalloproteinases (MMPs), the major mediators of extracellular matrix (ECM) degradation, is crucial to regulate ECM proteolysis, which is important in metastasis. This study examined the effects of 3 flavonoid-enriched fractions (a crude fraction, an anthocyanin-enriched fr...
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Lack of knowledge was also a barrier. Some lacked food and food preparation knowledge; others lacked nutrition knowledge. Several participants noted that they didn't know what to do with the new fruits and vegetables available at the grocery store. One said, "The thing is you go to [... the sto...
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Hypertension is a major risk factor for cardiovascular disease, the number one cause of disability and death in North America. Thus, strategies (e.g. diet modification, drugs) to manage hypertension are essential. Lowbush blueberries (Vaccinium angustifolium) are rich in polyphenolic antioxidants wh...
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