38 Wistar rats with a mean weight of 177 g were divided in 5 groups. Rats were inoculated i.t. with 0.5 ml of fluid (made up to a constant volume using saline solution) containing 2.5 mg of silica, but a variable amount of amniotic fluid (0, 0.125, 0.250, 0.375 or 0.500 ml). The rats were killed 72 ...

288 mice were divided into four groups and exposed to aerosols of P. haemolytica or S. aureus in four replicates. The numbers of bacteria were determined in the trachea and lungs of mice killed 0, 2, 4, 8, 12, 24, 48 and 72 hours after exposure. Bacterial deposition was greater in lungs than in trac...

A dog adopted as a stray in Spain and then brought to Canada 4 years prior to presentation was evaluated for polyarthritis. An electrophoresis showed a marked polyclonal gammopathy and synovial smears contained leishmanial organisms within macrophages.

The meconium aspiration syndrome is an important cause of respiratory distress in newborn infants. Alveolar macrophages (AMs) provide a first line of defense in the lower respiratory tract against inhaled pathogens and particles such as meconium. In this study, we examined the effect of meconium on ...

A Clydesdale mare was examined for weight loss, inappetence, ptyalism, and dysphagia. The main abnormality revealed by serum biochemistry was a marked hyperglobulinemia, and protein electrophoresis revealed a monoclonal gammopathy in the gamma region. The urine was positive for Bence Jones proteins....

The ability of infectious bursal disease virus (IBDV) serotypes 1 and 2, and the role of VP4 of both serotypes as well as the capacity of three IBDV intermediate serotype 1-specific vaccine strains to induce apoptosis in a chicken B-lymphocyte cell line, DT40, were investigated using the TUNEL techn...

Experiments were undertaken to examine the chymotrypsin sensitivity and trypsin sensitivity of 13 avian reoviruses, and to determine if there was any correlation with pathogenicity of some chicken reoviruses. A wide variation in the degree of sensitivity of avian reoviruses to chymotrypsin and tryps...