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Serotonin releases adenosine from primary afferent nerve terminals in the spinal cord
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The GABA8 receptor agonist (-)-baclofen and the 1,4-dihydropyridine CA2+ channel agonist Bay K 8644 modulate the GTP-binding protein G0 via different mechanisms
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Endogenous adenosine protects neurons but not astrosytes from hypoxic cell death
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Investigation of the effects of cranberry fractions on atherosclerosis in mice
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G protein modulation of calcium entry and transmitter release
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Adenosine A1 agonists stimulate the GTPase activity of G- and G0-type G-proteins in cortical membranes
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Adenosine A1 receptors inhibit necrosis and apoptosis induced by oxygen and glucose deprivation in cultured neurons
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Annals of the NY Academy of Sciences Conference entitled "Oxidative/Energy metabolism in neurodegenerative disorders"
The effects of individual fractions of lowbush (wild) blueberries (Vaccinium angustifolium) on primary cultured neurons after simulated ischemic stroke and oxidative stress.
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PEI Health Research Institute Forum
Involvement of adenosine in the analgesic effect of morphine and noradrenaline in the spinal cord
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Adenosine release from the spinal cord may mediate antinodideption by intracerebroventricular morphine
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5-Hydroxytryptamine releases adenosine from primary afferent nerve terminals in the spinal cord
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5-Hydroxytryptamine (serotonin, 5-HT) increased the release of endogenous adenosine from dorsal, but not ventral, spinal cord synaptosomes. This release was reduced by (i) the 5-HT receptor antagonist methysergide, (ii) removal of Ca2+ from the medium, (iii) inhibition of ecto-5'-nucleotidase a...
Morphine-evoked release of adenosine from the spinal cord occurs via a dipyridamole-sensitive carrier
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Adenosine agonist reduces hypoxia-ischemia induced cell death in the hippocampus of male rats
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The adenosine agonist CPA inhibits necrosis but promotes apoptosis induced by simulated ischemia in neuronal cultures
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Desensitization of adenosine receptors during brain hypoxia limits the neuroprotective effects of adenosine
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Biochemical evidence that dihydropyridine and BABA8 receptors interact with G0 and G respectively
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Effect of intrathecal pretreatment with neurotoxins on adenosine release from rat spinal cord synaptosomes
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Morphine releases adenosine from capsaicin-sensitive neurons in the spinal cord
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Adenosine A1 receptor agonists prevent delayed neuronal death following ischemia
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Adenosine A1 receptors precondition the rat brain against hypoxia-ischemia damage one day later
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Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons
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This study was designed to examine the ability of pertussis toxin to block various responses due to (-)-baclofen in cultured cerebellar granule neurons of the rat. Treatment with pertussis toxin for 3 h markedly reduced the ability of (-)-baclofen to stimulate GTPase in membranes, and its ability to...
Pertussis toxin inhibits morphine-induced release of adenosine from the spinal cord
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Activation of adenosine receptors protects neurons from ischemia-induced death
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Biochemical evidence that GTP binding proteins are directly coupled to dihydropyridine receptors
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The role of purines in nociception
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The preceding review indicates that there is convincing evidence for the presence of adenosine in and release of adenosine from capsaicin-sensitive small diameter primary afferent neurons in the spinal cord (Fig. 1). Within the dorsal spinal cord, adenosine inhibits the transmission of nociceptive i...