Results

[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
This study was designed to examine the ability of pertussis toxin to block various responses due to (-)-baclofen in cultured cerebellar granule neurons of the rat. Treatment with pertussis toxin for 3 h markedly reduced the ability of (-)-baclofen to stimulate GTPase in membranes, and its ability to...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Substance P (SP), injected intrathecally, produced a dose-related increase in responsiveness (hyperalgesia) in a pressure test for nociceptive thresholds. Pretreatment with two doses of SP produced complete desensitization to this response but did not alter base-line responsiveness. The hyperalgesic...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
We have investigated the potential role of a bi-directional nucleoside carrier in the release of endogenous adenosine from spinal cord synaptosomes by examining the effects of dipyridamole and nitrobenzylthioinosine (NBI) on evoked release of adenosine. When 40 pmol adenosine were added to synaptoso...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Regulation of the matrix metalloproteinases (MMPs) is crucial to regulate extracellular matrix (ECM) proteolysis which is important in metastasis. This study investigated the mechanism(s) by which three flavonoid-enriched fractions from lowbush blueberry (Vaccinium angustifolium) down-regulate MMP a...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Oxidative stress is an important element in the etiology of ischemic stroke. Lowbush blueberries (Vaccinium angustifolium Aiton) have a high antioxidant capacity and thus we determined whether consumption of lowbush blueberries would protect neurons from stroke-induced damage. Rats were fed AIN-93G ...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Regulation of the matrix metalloproteinases (MMPs), the major mediators of extracellular matrix (ECM) degradation, is crucial to regulate ECM proteolysis, which is important in metastasis. This study examined the effects of 3 flavonoid-enriched fractions (a crude fraction, an anthocyanin-enriched fr...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Proanthocyanidin-rich extracts were prepared by fractionation of the fruit of the North American cranberry (Vaccinium macrocarpon). In vitro growth inhibition assays in eight tumor cell lines showed that selected fractions inhibited the growth of H460 lung tumors, HT-29 colon and K562 leukemia cells...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Hypertension is a major risk factor for cardiovascular disease, the number one cause of disability and death in North America. Thus, strategies (e.g. diet modification, drugs) to manage hypertension are essential. Lowbush blueberries (Vaccinium angustifolium) are rich in polyphenolic antioxidants wh...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
Beneficial health effects of cranberries (CBs) and wild blueberries (BBs), such as reduced levels of oxidative stress, have been demonstrated in feeding studies. These Vaccinium berries contain high levels of flavonoids; however, the bioavailability of flavonoids is generally low. We investigated th...
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]
[Page generation failure. The bibliography processor requires a browser with Javascript enabled.]