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Caprine hemal nodes were studied by transmission electron microscopy after glutaraldehyde fixation and epoxy resin embedding. Hemal node macrophages were observed to be engaged in erythrophagocytosis. In the early stages of endocytosis, intact erythrocytes were contained in some of the heterophagic ...
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A fixative composed of 1% w/v osmium tetroxide dissolved in a fluorocarbon (FC-72) was used to perfusion-fix rat blood vessels for this ultrastructural study. With non-aqueous fixation, the lumenal surfaces of endothelial cells in cardiac and skeletal muscles retained an extracellular coat which was...
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A syndrome characterized by anemia, erythrocyte dyscrasia, low body weight, and hypothyroidism was observed in 8 llamas (Lama glama). At initial examination (1 to 23 months of age; median, 7.5 months), llamas (3 males, 5 females) were markedly underweight (29 to 55 kg; median, 36 kg) and anemic (PCV...
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Physiological and ultrastructural assessment of changes in the walls of venules in the rat cremaster muscle after administration of histamine indicates that pericytes have essential roles in the normal functioning of venules during inflammation. Fluorescein-labelled albumin was used to quantitate ma...
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The ultrastructure of healthy skin mucus of Salmo salar was examined and the possible changes induced by infestation with Lepeophtheirus salmonis investigated. Until recently, there have been no methods for reliable preservation of fish skin mucus. A fixation method that uses a non-aqueous solvent a...
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Interleukin 2 (IL-2) mediates the regression of metastatic cancer, but its clinical use is limited by associated toxicities including hepatic dysfunction. To determine the mechanism for IL-2-induced hepatic dysfunction, we hypothesized that IL-2 activation of Kupffer cells causes leukocyte-endotheli...
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Neonatal and mature bovine lungs were examined ultrastructurally to quantitatively assess pericyte envelopment of gas exchange capillaries and proximities of pericyte margins to endothelial cell junctions. Pericytes were observed on 91% of the cross-sectioned capillary profiles examined, with 18 and...