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The pharmacokinetics of steady-state oral sustained-release morphine sulphate (OSRMS) were studied in dogs. Beagles (n = 6) were randomly assigned to one of two treatment groups. Treatments included 15 mg OSRMS every 8 h for 4 days, or 15 mg OSRMS every 12 h for 4 days. Serum samples, drawn at inter...
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Isoflurane is the most recently available inhalational anaesthetic agent on the market. Although there have been few clinical trials comparing its use to halothane and methoxyflurane, the pharmacology of the agent suggests certain situations in which it may be the preferred agent. These include avia...
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Three hundred and twenty-two Canadian animal health technologists (AHTs) were surveyed to determine their attitudes toward postoperative pain management in dogs and cats following 6 surgical procedures, their concerns regarding the use of opioid analgesics, and their role within veterinary practices...
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Using random allocation, 92 clinically healthy dogs were restrained chemically using fentany/droperidol, and 71 using oxymorphone/acepromazine, for radiography. Questionnaires completed by the radiology department revealed no significant differences between the drug combinations either in effectiven...
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Four hundred and seventeen Canadian veterinarians were surveyed to determine their postoperative use of analgesics in dogs and cats following 6 categories of surgeries, and their opinion toward pain perception and perceived complications associated with the postoperative use of potent opioid analges...
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The pharmacokinetics of single-dose morphine sulphate (MS) administered intravenously (i.v.) and intramuscularly (i.m.) and of oral sustained-release morphine sulphate (OSRMS) were studied in dogs. Beagles (n = 6) were randomly assigned to six treatment groups using a Latin square design. Treatments...
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Nine healthy mixed-breed dogs weighing between 15 and 28 kg were anaesthetized with 33% oxygen, 67% nitrous oxide and halothane. Oxygen flow rates of 10, 20 and 30 ml/kg per minute were administered with appropriate nitrous oxide flow rates for three consecutive 45-minute periods. Inspired oxygen co...
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Four hundred and seventeen Canadian veterinarians were surveyed to determine their postoperative use of analgesics in dogs and cats following 6 surgical procedures, and to determine their opinions toward pain perception and perceived complications associated with the postoperative use of potent opio...
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This study investigated the pharmacokinetics of morphine sulphate in an injectable chitosan-based gel. Gels were made from a combination of N-O-carboxymethylchitosan (NOCC) and chitosan and were easily injectable via a 22 gauge needle and appeared stable during long-term storage. Groups of six beagl...
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The pharmacokinetics and bioavailability (F) of single dose sustained release morphine sulfate (OSRMS) and nonsustained release morphine sulfate (NSRMS) were compared to each other and to a bolus injection of morphine sulfate (MS) intravenously (i.v.) in dogs. Beagles (n = 6) were randomly assigned ...
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A retrospective cross-sectional survey of dog-owning veterinary clients was undertaken in 1996 in three Canadian provinces (New Brunswick, Nova Scotia, and Prince Edward Island) to generate a population of dogs for future use in a more detailed survey on canine behaviour. The questionnaire was desig...
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A detailed telephone survey of dog owners was undertaken in 1996 to determine the risk factors for biting behaviour of dogs in a household setting. Individuals were selected from a cross-sectional population of veterinary clientele in the Canadian provinces of New Brunswick, Nova Scotia, and Prince ...
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The characteristics of 227 biting dogs, their homes, and their victims were gathered in a detailed telephone survey of general veterinary clientele in the Canadian provinces of New Brunswick, Nova Scotia, and Prince Edward Island. All of the dogs had bitten either someone living in the same househol...